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홈

협진정보

협진표준임상진료지침

협진정보

협진표준임상진료지침

협진표준임상진료지침

C00-D48

Ⅱ. 신생물

암 수술 후 통증 환자의 주 증상 개선을 위하여 일상관리보다 침 치료 및 일상관리의 병행을 고려할 수 있다.

일상관리에는 지지요법 및 대증 요법이 포함된다. 혈자리로는 수술 부위 주변 아시혈, 합곡(LI4), 태충(LR3), 족삼리(ST36), 양릉천(GB34) 등을 고려할 수 있다. 치료기간은 보통 수술 전 3일에서 수술 후 7일 정도 치료한다.

C/Low

  • Poulain P, Léandri EP, Laplanche A, Montange F, Bouzy J, Truffa-Bachi J. Electroacupuncture Analgesia in Major Abdominal and Pelvic Surgery: A Randomised Study. Acupuncture in Medicine.
    1997;15(1):10–3. Link

  • 贺必梅, 李万山, 李万瑶. 头针超前镇痛对肠癌患者术后硬膜外吗啡镇痛的影响, 中国针灸. 2007;27(5):369-71. Link

  • Pfister DG, Cassileth BR, Deng GE, Yeung KS, Lee JS, Garrity D, et al. Acupuncture for Pain and Dysfunction After Neck Dissection: Results of a Randomized Controlled Trial. Journal of Clinical Oncology. 2010;28(15):2565–70. Link

  • 刘莉莉，樊永平，颉泽华, 安立新, 赵百孝. 电针对幕上肿瘤切除术患者围手术期中医症状的影响. 中国中医基础医学杂志. 2012;18(04):424-7. Link

  • Quinlan-Woodward J, Gode A, Dusek J, Reinstein A, Johnson J, Sendelbach S. Assessing the Impact
    of Acupuncture on Pain, Nausea, Anxiety, and Coping in Women Undergoing a Mastectomy. Oncology Nursing Forum. 2016;43(6):725–32. Link

  • Poulain P, Léandri EP, Laplanche A, Montange F, Bouzy J, Truffa-Bachi J. Electroacupuncture Analgesia in Major Abdominal and Pelvic Surgery: A Randomised Study. Acupuncture in Medicine.
    1997;15(1):10–3. Link

  • 贺必梅, 李万山, 李万瑶. 头针超前镇痛对肠癌患者术后硬膜外吗啡镇痛的影响, 中国针灸. 2007;27(5):369-71. Link

  • Pfister DG, Cassileth BR, Deng GE, Yeung KS, Lee JS, Garrity D, et al. Acupuncture for Pain and Dysfunction After Neck Dissection: Results of a Randomized Controlled Trial. Journal of Clinical Oncology. 2010;28(15):2565–70. Link

  • 刘莉莉，樊永平，颉泽华, 安立新, 赵百孝. 电针对幕上肿瘤切除术患者围手术期中医症状的影响. 中国中医基础医学杂志. 2012;18(04):424-7. Link

  • Quinlan-Woodward J, Gode A, Dusek J, Reinstein A, Johnson J, Sendelbach S. Assessing the Impact
    of Acupuncture on Pain, Nausea, Anxiety, and Coping in Women Undergoing a Mastectomy. Oncology Nursing Forum. 2016;43(6):725–32. Link

암 수술 후 통증 환자의 주 증상 개선을 위하여 침 치료를 고려해야 한다.

혈자리로는 수술 부위 주변 아시혈, 합곡(LI4), 태충(LR3), 족삼리(ST36), 양릉천(GB34) 등을 고려할 수 있다. 치료기간은 보통 수술 전 3일에서 수술 후 7일 정도 치료한다.

B/Moderate

  • Wong RHL, Lee TW, Sihoe ADL, Wan IYP, Ng CSH, Chan SKC, et al. Analgesic Effect of
    Electroacupuncture in Postthoracotomy Pain: A Prospective Randomized Trial. The Annals of
    Thoracic Surgery. 2006;81(6):2031–6. Link

  • Deng G, Rusch V, Vickers A, Malhotra V, Ginex P, Downey R, et al. Randomized controlled trial of a special acupuncture technique for pain after thoracotomy. The Journal of Thoracic and Cardiovascular Surgery. 2008;136(6):1464–9. Link

  • Ntritsou V, Mavrommatis C, Kostoglou C, Dimitriadis G, Tziris N, Zagka P, et al. Effect of Perioperative Electroacupuncture as An Adjunctive Therapy on Postoperative Analgesia with Tramadol and Ketamine in Prostatectomy: A Randomised Sham-Controlled Single-Blind Trial. Acupuncture in Medicine. 2014;32(3):215–22. Link

  • Wong RHL, Lee TW, Sihoe ADL, Wan IYP, Ng CSH, Chan SKC, et al. Analgesic Effect of
    Electroacupuncture in Postthoracotomy Pain: A Prospective Randomized Trial. The Annals of
    Thoracic Surgery. 2006;81(6):2031–6. Link

  • Deng G, Rusch V, Vickers A, Malhotra V, Ginex P, Downey R, et al. Randomized controlled trial of a special acupuncture technique for pain after thoracotomy. The Journal of Thoracic and Cardiovascular Surgery. 2008;136(6):1464–9. Link

  • Ntritsou V, Mavrommatis C, Kostoglou C, Dimitriadis G, Tziris N, Zagka P, et al. Effect of Perioperative Electroacupuncture as An Adjunctive Therapy on Postoperative Analgesia with Tramadol and Ketamine in Prostatectomy: A Randomised Sham-Controlled Single-Blind Trial. Acupuncture in Medicine. 2014;32(3):215–22. Link

암 수술 후 장마비 환자의 주 증상 개선을 위하여 대건중탕을 고려해야 한다.

대건중탕은 하루 3회씩 수술 전 3일부터 수술 후 3개월까지 복용할 수 있다.

B/Moderate

  • Akamaru Y, Takahashi T, Nishida T, Omori T, Nishikawa K, Mikata S, et al. Effects of Daikenchuto, a
    Japanese Herb, on Intestinal Motility After Total Gastrectomy: a Prospective Randomized Trial. Journal
    of Gastrointestinal Surgery. 2015;19(3):467–72. Link

  • Katsuno H, Maeda K, Kaiho T, Kunieda K, Funahashi K, Sakamoto J, et al. Clinical efficacy of Daikenchuto
    for gastrointestinal dysfunction following colon surgery: a randomized, double-blind, multicenter, placebo-controlled study (JFMC39-0902). Japanese Journal of Clinical Oncology. 2015;45(7):650–6. Link

  • Yoshikawa K, Shimada M, Wakabayashi G, Ishida K, Kaiho T, Kitagawa Y, et al. Effect of Daikenchuto,
    a Traditional Japanese Herbal Medicine, after Total Gastrectomy for Gastric Cancer: A Multicenter,
    Randomized, Double-Blind, Placebo-Controlled, Phase II Trial. Journal of the American College of Surgeons. 2015;221(2):571–8. Link

  • Katsuno H, Maeda K, Ohya M, Yoshioka K, Tsunoda A, Koda K, et al. Clinical pharmacology of daikenchuto
    assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study). Journal of Gastroenterology. 2016;51(3):222–9. Link

  • Okada K-ichi, Kawai M, Hirono S, Fujii T, Kodera Y, Sho M, et al. Evaluation of the efficacy of daikenchuto
    (TJ -100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial. Surgery. 2016;159(5):1333–41. Link

  • Kono T, Shimada M, Nishi M, Morine Y, Yoshikawa K, Katsuno H, et al. Daikenchuto accelerates the
    recovery from prolonged postoperative ileus after open abdominal surgery: a subgroup analysis of three
    randomized controlled trials. Surgery Today. 2019;49(8):704–11. Link

  • Akamaru Y, Takahashi T, Nishida T, Omori T, Nishikawa K, Mikata S, et al. Effects of Daikenchuto, a
    Japanese Herb, on Intestinal Motility After Total Gastrectomy: a Prospective Randomized Trial. Journal
    of Gastrointestinal Surgery. 2015;19(3):467–72. Link

  • Katsuno H, Maeda K, Kaiho T, Kunieda K, Funahashi K, Sakamoto J, et al. Clinical efficacy of Daikenchuto
    for gastrointestinal dysfunction following colon surgery: a randomized, double-blind, multicenter, placebo-controlled study (JFMC39-0902). Japanese Journal of Clinical Oncology. 2015;45(7):650–6. Link

  • Yoshikawa K, Shimada M, Wakabayashi G, Ishida K, Kaiho T, Kitagawa Y, et al. Effect of Daikenchuto,
    a Traditional Japanese Herbal Medicine, after Total Gastrectomy for Gastric Cancer: A Multicenter,
    Randomized, Double-Blind, Placebo-Controlled, Phase II Trial. Journal of the American College of Surgeons. 2015;221(2):571–8. Link

  • Katsuno H, Maeda K, Ohya M, Yoshioka K, Tsunoda A, Koda K, et al. Clinical pharmacology of daikenchuto
    assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study). Journal of Gastroenterology. 2016;51(3):222–9. Link

  • Okada K-ichi, Kawai M, Hirono S, Fujii T, Kodera Y, Sho M, et al. Evaluation of the efficacy of daikenchuto
    (TJ -100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial. Surgery. 2016;159(5):1333–41. Link

  • Kono T, Shimada M, Nishi M, Morine Y, Yoshikawa K, Katsuno H, et al. Daikenchuto accelerates the
    recovery from prolonged postoperative ileus after open abdominal surgery: a subgroup analysis of three
    randomized controlled trials. Surgery Today. 2019;49(8):704–11. Link

암 수술 후 장마비 환자의 주 증상 개선을 위하여 한약 치료를 고려할 수 있다.

한약치료는 하루 3회씩 수술 전 3일부터 수술 후 3개월까지 복용할 수 있다.

C/Low

  • Akamaru Y, Takahashi T, Nishida T, Omori T, Nishikawa K, Mikata S, et al. Effects of Daikenchuto,
    a Japanese Herb, on Intestinal Motility After Total Gastrectomy: a Prospective Randomized Trial. Journal of Gastrointestinal Surgery. 2015;19(3):467–72. Link

  • Katsuno H, Maeda K, Kaiho T, Kunieda K, Funahashi K, Sakamoto J, et al. Clinical efficacy of Daikenchuto for gastrointestinal dysfunction following colon surgery: a randomized, double-blind, multicenter, placebo-controlled study (JFMC39-0902). Japanese Journal of Clinical Oncology. 2015;45(7):650–6. Link

  • Yoshikawa K, Shimada M, Wakabayashi G, Ishida K, Kaiho T, Kitagawa Y, et al. Effect of Daikenchuto,
    a Traditional Japanese Herbal Medicine, after Total Gastrectomy for Gastric Cancer: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase II Trial. Journal of the American College of Surgeons. 2015;221(2):571–8. Link

  • Katsuno H, Maeda K, Ohya M, Yoshioka K, Tsunoda A, Koda K, et al. Clinical pharmacology of daikenchuto assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study). Journal of Gastroenterology. 2016;51(3):222–9. Link

  • Okada K-ichi, Kawai M, Hirono S, Fujii T, Kodera Y, Sho M, et al. Evaluation of the efficacy of daikenchuto (TJ -100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial. Surgery. 2016;159(5):1333–41. Link

  • 邹先雄. 中西医结合治疗结直肠癌术后肠麻痹 46 例. 河南中医. 2016;4:655-7. Link

  • Kono T, Shimada M, Nishi M, Morine Y, Yoshikawa K, Katsuno H, et al. Daikenchuto accelerates the recovery from prolonged postoperative ileus after open abdominal surgery: a subgroup analysis of three randomized controlled trials. Surgery Today. 2019;49(8):704–11. Link

  • Akamaru Y, Takahashi T, Nishida T, Omori T, Nishikawa K, Mikata S, et al. Effects of Daikenchuto,
    a Japanese Herb, on Intestinal Motility After Total Gastrectomy: a Prospective Randomized Trial. Journal of Gastrointestinal Surgery. 2015;19(3):467–72. Link

  • Katsuno H, Maeda K, Kaiho T, Kunieda K, Funahashi K, Sakamoto J, et al. Clinical efficacy of Daikenchuto for gastrointestinal dysfunction following colon surgery: a randomized, double-blind, multicenter, placebo-controlled study (JFMC39-0902). Japanese Journal of Clinical Oncology. 2015;45(7):650–6. Link

  • Yoshikawa K, Shimada M, Wakabayashi G, Ishida K, Kaiho T, Kitagawa Y, et al. Effect of Daikenchuto,
    a Traditional Japanese Herbal Medicine, after Total Gastrectomy for Gastric Cancer: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase II Trial. Journal of the American College of Surgeons. 2015;221(2):571–8. Link

  • Katsuno H, Maeda K, Ohya M, Yoshioka K, Tsunoda A, Koda K, et al. Clinical pharmacology of daikenchuto assessed by transit analysis using radiopaque markers in patients with colon cancer undergoing open surgery: a multicenter double-blind randomized placebo-controlled study (JFMC39-0902 additional study). Journal of Gastroenterology. 2016;51(3):222–9. Link

  • Okada K-ichi, Kawai M, Hirono S, Fujii T, Kodera Y, Sho M, et al. Evaluation of the efficacy of daikenchuto (TJ -100) for the prevention of paralytic ileus after pancreaticoduodenectomy: A multicenter, double-blind, randomized, placebo-controlled trial. Surgery. 2016;159(5):1333–41. Link

  • 邹先雄. 中西医结合治疗结直肠癌术后肠麻痹 46 例. 河南中医. 2016;4:655-7. Link

  • Kono T, Shimada M, Nishi M, Morine Y, Yoshikawa K, Katsuno H, et al. Daikenchuto accelerates the recovery from prolonged postoperative ileus after open abdominal surgery: a subgroup analysis of three randomized controlled trials. Surgery Today. 2019;49(8):704–11. Link

암 수술 후 장마비 환자의 주 증상 개선을 위하여 침 치료를 사용할 것을 권고한다.

혈자리로는 족삼리(ST36), 삼음교(SP6), 합곡(LI4), 지구(TE6), 내관(PC6)를 고려할 수 있다. 치료기간은 보통 수술 후 매일 1주정도 치료한다.

A/High

  • Deng G, Wong WD, Guillem J, Chan Y, Affuso T, Yeung KS, et al. A Phase II, Randomized, Controlled Trial of Acupuncture for Reduction of Postcolectomy Ileus. Annals of Surgical Oncology. 2013;20(4):1164–9. Link

  • Ng SSM, Leung WW, Mak TWC, Hon SSF, Li JCM, Wong CYN, et al. Electroacupuncture Reduces
    Duration of Postoperative Ileus After Laparoscopic Surgery for Colorectal Cancer. Gastroenterology.
    2013;144(2). Link

  • Deng G, Wong WD, Guillem J, Chan Y, Affuso T, Yeung KS, et al. A Phase II, Randomized, Controlled Trial of Acupuncture for Reduction of Postcolectomy Ileus. Annals of Surgical Oncology. 2013;20(4):1164–9. Link

  • Ng SSM, Leung WW, Mak TWC, Hon SSF, Li JCM, Wong CYN, et al. Electroacupuncture Reduces
    Duration of Postoperative Ileus After Laparoscopic Surgery for Colorectal Cancer. Gastroenterology.
    2013;144(2). Link

방사선치료 유발 구강건조증 환자의 주 증상 개선을 위하여 일상관리 또는 무처치 보다 자음생진의 효능을 가진 한약 치료를 고려할 수 있다.

방사선유발 구강건조증은 통상의학의 진단 및 치료와의 병행을 고려해야 한다. 일상관리에는 구강관리교육 등이 포함된다. 처방으로는 증액탕, 가미증액탕, 사삼맥문동탕 등을 사용할 수 있으며 단방으로는 생지황, 천문동, 맥문동, 사삼 등을 응용할 수 있다. 치료기간은 4주-7주 복용한다.

C/Low

  • 李华, 成惠贞, 胡艳文, 田大龙, 喻志冲, 王贺芳, et al. 中医治疗头颈肿瘤放疗中口干症的疗效观察. 辽宁中医杂志. 2009;8:1355-7. Link

  • 蒋泽先, 邱嘉旋, 钱永, 钱永, 罗秋萍. 中药治疗头颈肿瘤放疗后口干症的疗效观察. 江西医学院学报. 2005;3:24-5+30. Link

  • 朱久育, 贾建伟, 陈国荣. 中药治疗放疗引起的口腔溃疡和口干的体会. 现代口腔医学杂志. 2001;1:79. Link

  • 张才友, 曾春生, 洪明晃, 张爱兰, 崔念基, 陈福进. 中药治疗鼻咽癌放疗后口干燥症的临床观察. 中国肿瘤临床与康复. 2011;4:374-6. Link

  • 王记南, 张健, 李修炜. 加味增液汤治疗鼻咽癌患者放疗后口干症的疗效. 中国卫生标准管理. 2015;31:123-5. Link

  • 张云芳, 张明. 加味增液汤治疗鼻咽癌放疗后口干症的疗效观察. 现代中西医结合杂志. 2015;3:308-9. Link

  • 杨小玲, 李俊枫, 吴立. 增液汤治疗放射性口腔干燥症30例观察. 实用中医药杂志. 2014;5:398. Link

  • 何影. 柴芍地黄汤对头颈恶性肿瘤患者放射性口干和放疗急副反应疗效的初步观察. 右江医学. 2018;3:278-81. Link

  • 王庆伟, 刘宏, 乔乃安, 程玉峰, 刘月欣. 活血生津中药对头颈部肿瘤患者放疗中唾液腺的影响.中国中西医结合杂志. 1998;11:662-4. Link

  • 张强, 丛景, 李道乾, 王翠花, 李强. 清热活血生津方对头颈部放疗唾液腺功能保护作用临床研 究. 中國中医急症. 2001;2:82-3. Link

  • 马新英, 张鑫, 支艳, 东文霞, 刘素杰. 清肺养胃方防治急性放射性口腔炎及口干症临床观察. 中国中医药信息杂志. 2012;4:65-6. Link

  • 曹恒军. 生津活血中药在头颈部放疗中对涎腺功能影响的研究. 口腔医学. 2009;6:315-8. Link

  • 姚德蛟, 蔡懿, 陈玉. 生津活血止渴方防治鼻咽癌放疗急性口咽反应临床观察. 中國中医急症. 2013;9:1594-5. Link

  • 曹裕杰, 蔡传书, 魏斌, 陈陵. 酸甘化阴法治疗鼻咽癌放疗后口干症疗效观察. 中国医药导报. 2009;14:50-1. Link

  • 王晓萍, 傅辰春, 张新良, 丁巍, 赵云艳, 刘丽, et al. 黄连生地方防治放射性唾液腺损伤的临床观察. 临床肿瘤学杂志. 2011;7:597-601. Link

  • 李华, 成惠贞, 胡艳文, 田大龙, 喻志冲, 王贺芳, et al. 中医治疗头颈肿瘤放疗中口干症的疗效观察. 辽宁中医杂志. 2009;8:1355-7. Link

  • 蒋泽先, 邱嘉旋, 钱永, 钱永, 罗秋萍. 中药治疗头颈肿瘤放疗后口干症的疗效观察. 江西医学院学报. 2005;3:24-5+30. Link

  • 朱久育, 贾建伟, 陈国荣. 中药治疗放疗引起的口腔溃疡和口干的体会. 现代口腔医学杂志. 2001;1:79. Link

  • 张才友, 曾春生, 洪明晃, 张爱兰, 崔念基, 陈福进. 中药治疗鼻咽癌放疗后口干燥症的临床观察. 中国肿瘤临床与康复. 2011;4:374-6. Link

  • 王记南, 张健, 李修炜. 加味增液汤治疗鼻咽癌患者放疗后口干症的疗效. 中国卫生标准管理. 2015;31:123-5. Link

  • 张云芳, 张明. 加味增液汤治疗鼻咽癌放疗后口干症的疗效观察. 现代中西医结合杂志. 2015;3:308-9. Link

  • 杨小玲, 李俊枫, 吴立. 增液汤治疗放射性口腔干燥症30例观察. 实用中医药杂志. 2014;5:398. Link

  • 何影. 柴芍地黄汤对头颈恶性肿瘤患者放射性口干和放疗急副反应疗效的初步观察. 右江医学. 2018;3:278-81. Link

  • 王庆伟, 刘宏, 乔乃安, 程玉峰, 刘月欣. 活血生津中药对头颈部肿瘤患者放疗中唾液腺的影响.中国中西医结合杂志. 1998;11:662-4. Link

  • 张强, 丛景, 李道乾, 王翠花, 李强. 清热活血生津方对头颈部放疗唾液腺功能保护作用临床研 究. 中國中医急症. 2001;2:82-3. Link

  • 马新英, 张鑫, 支艳, 东文霞, 刘素杰. 清肺养胃方防治急性放射性口腔炎及口干症临床观察. 中国中医药信息杂志. 2012;4:65-6. Link

  • 曹恒军. 生津活血中药在头颈部放疗中对涎腺功能影响的研究. 口腔医学. 2009;6:315-8. Link

  • 姚德蛟, 蔡懿, 陈玉. 生津活血止渴方防治鼻咽癌放疗急性口咽反应临床观察. 中國中医急症. 2013;9:1594-5. Link

  • 曹裕杰, 蔡传书, 魏斌, 陈陵. 酸甘化阴法治疗鼻咽癌放疗后口干症疗效观察. 中国医药导报. 2009;14:50-1. Link

  • 王晓萍, 傅辰春, 张新良, 丁巍, 赵云艳, 刘丽, et al. 黄连生地方防治放射性唾液腺损伤的临床观察. 临床肿瘤学杂志. 2011;7:597-601. Link

방사선치료 유발 구강건조증 환자의 주 증상 개선을 위하여 일상관리보다 침 치료를 고려해야 한다.

방사선치료 유발 구강건조증은 통상의학의 진단 및 치료와의 병행을 고려해야 한다. 일상관리에는 구강관리교육 등이 포함된다. 혈자리로는 협거(ST6), 승장(CV24), 염천(CV23), 합곡(LI4), 족삼리(ST36), 삼음교(SP6), 이침(신문, 영점)을 고려할 수 있다. 치료기간은 6주-12주 치료한다.

B/Moderate

  • Simcock R, Fallowfield L, Monson K, Solis-Trapala I, Parlour L, Langridge C, et al. ARIX: A randomised trial of acupuncture v oral care sessions in patients with chronic xerostomia following treatment of head and neck cancer. Annals of Oncology. 2013;24(3):776–83. Link

  • Meng Z, Garcia MK, Hu C, Chiang J, Chambers M, Rosenthal DI, et al. Randomized controlled trial of acupuncture for prevention of radiation-induced xerostomia among patients with nasopharyngeal
    carcinoma. Cancer. 2012;118(13):3337–44. Link

  • 赵伟鹏, 姜欣, 黄金昶. 针刺治疗放疗后口干症疗效观察. 中国临床医生杂志. 2015;3:80-2. Link

  • Garcia MK, Meng Z, Rosenthal DI, Shen Y, Chambers M, Yang P, et al. Effect of True and Sham Acupuncture on Radiation-Induced Xerostomia Among Patients With Head and Neck Cancer. JAMA Network Open. 2019;2(12). Link

  • Simcock R, Fallowfield L, Monson K, Solis-Trapala I, Parlour L, Langridge C, et al. ARIX: A randomised trial of acupuncture v oral care sessions in patients with chronic xerostomia following treatment of head and neck cancer. Annals of Oncology. 2013;24(3):776–83. Link

  • Meng Z, Garcia MK, Hu C, Chiang J, Chambers M, Rosenthal DI, et al. Randomized controlled trial of acupuncture for prevention of radiation-induced xerostomia among patients with nasopharyngeal
    carcinoma. Cancer. 2012;118(13):3337–44. Link

  • 赵伟鹏, 姜欣, 黄金昶. 针刺治疗放疗后口干症疗效观察. 中国临床医生杂志. 2015;3:80-2. Link

  • Garcia MK, Meng Z, Rosenthal DI, Shen Y, Chambers M, Yang P, et al. Effect of True and Sham Acupuncture on Radiation-Induced Xerostomia Among Patients With Head and Neck Cancer. JAMA Network Open. 2019;2(12). Link

방사선치료 유발 구강건조증 환자의 주 증상 개선을 위하여 침 치료를 고려해야 한다.

방사선치료 유발 구강건조증은 통상의학의 진단 및 치료와의 병행을 고려해야 한다. 혈자리로는 협거(ST6), 승장(CV24), 염천(CV23), 합곡(LI4), 족삼리(ST36), 삼음교(SP6), 이침(신문, 영점)을 고려할 수 있다. 치료기간은 6주-12주 치료한다.

B/Moderate

  • Meng Z, Kay Garcia M, Hu C, Chiang J, Chambers M, Rosenthal DI, et al. Sham-controlled, randomised, feasibility trial of acupuncture for prevention of radiation-induced xerostomia among patients with nasopharyngeal carcinoma. European Journal of Cancer. 2012;48(11):1692–9. Link

  • ANDERSEN S, MACHIN D. Acupuncture treatment of patients with radiation-induced xerostomia. Oral Oncology. 1996;33(2):146–7. Link

  • Cho JH, Chung WK, Kang W, Choi SM, Cho CK, Son CG. Manual Acupuncture Improved Quality of Life in Cancer Patients with Radiation-Induced Xerostomia. The Journal of Alternative and Complementary Medicine. 2008;14(5):523–6. Link

  • Garcia MK, Meng Z, Rosenthal DI, Shen Y, Chambers M, Yang P, et al. Effect of True and Sham Acupuncture on Radiation-Induced Xerostomia Among Patients With Head and Neck Cancer. JAMA Network Open. 2019;2(12). Link

  • Meng Z, Kay Garcia M, Hu C, Chiang J, Chambers M, Rosenthal DI, et al. Sham-controlled, randomised, feasibility trial of acupuncture for prevention of radiation-induced xerostomia among patients with nasopharyngeal carcinoma. European Journal of Cancer. 2012;48(11):1692–9. Link

  • ANDERSEN S, MACHIN D. Acupuncture treatment of patients with radiation-induced xerostomia. Oral Oncology. 1996;33(2):146–7. Link

  • Cho JH, Chung WK, Kang W, Choi SM, Cho CK, Son CG. Manual Acupuncture Improved Quality of Life in Cancer Patients with Radiation-Induced Xerostomia. The Journal of Alternative and Complementary Medicine. 2008;14(5):523–6. Link

  • Garcia MK, Meng Z, Rosenthal DI, Shen Y, Chambers M, Yang P, et al. Effect of True and Sham Acupuncture on Radiation-Induced Xerostomia Among Patients With Head and Neck Cancer. JAMA Network Open. 2019;2(12). Link

항암화학요법 유발 말초신경병증 환자의 주 증상 개선을 위하여 일상관리 또는 무처치보다 한약 치료를 고려해야 한다.

항암화학요법 유발 말초신경병증이 발현되었을 때부터 가급적 조기에 치료를 시작하는 것을 권장한다. 일상관리에는 대증지지요법과 재활치료 등이 포함된다. 항암화학요법 유발 말초신경병증의 치료를 위한 한약치료처방은 당귀사역탕, 익기활혈탕, 온경화혈통비방 등을 고려할 수 있다. 4-12주간 복용한다.

B/Moderate

  • 焦蕉, 郑路丹, 黎月恒, 李东芳, 唐继云. 温经和血通痹方防治奥沙利铂化疗后周围神经毒性的临床观察. 云南中医中药杂志. 2019;4:28-30. Link

  • 丁蓉, 霍介格, 汪悦. 当归四逆汤防治奥沙利铂周围神经毒性的临床观察. 南京中医药大学学报. 2014;5:432-3. Link

  • 谢邦翔. 益气活血方治疗化疗导致周围神经病变的效果分析. 中外医学研究. 2018;36:118-9. Link

  • 焦蕉, 郑路丹, 黎月恒, 李东芳, 唐继云. 温经和血通痹方防治奥沙利铂化疗后周围神经毒性的临床观察. 云南中医中药杂志. 2019;4:28-30. Link

  • 丁蓉, 霍介格, 汪悦. 当归四逆汤防治奥沙利铂周围神经毒性的临床观察. 南京中医药大学学报. 2014;5:432-3. Link

  • 谢邦翔. 益气活血方治疗化疗导致周围神经病变的效果分析. 中外医学研究. 2018;36:118-9. Link

항암화학요법 유발 말초신경병증 환자의 주 증상 예방을 위하여 일상관리 또는 무처치보다 황기계지오물탕을 고려할 수 있다.

일상관리에는 대증지지요법과 재활치료가 포함된다. 복용방법은 일반적으로 항암화학요법 시작 전에 복용을 시작하여 하루2회-3회씩 8주-24주간 복용한다.

C/Low

  • Yuan L, Hui-juan G, Jin-chang H, Xiao-qin W. Clinical study of Jiawei Huangqi Guizhi Wuwu Decoction in preventing and treating peripheral neuro-sensory toxicity caused by oxaliplatin. Chinese Journal of Integrative Medicine. 2006;12(1):19–23. Link

  • 刘慧, 周之毅, 吴丽英, 王文海, 周荣耀, 黄建平, et al. 黄芪桂枝五物汤治疗奥沙利铂周围神经毒性的临床观察. 上海中医药杂志. 2011;3:44-7. Link

  • 徐先容. 黄芪桂枝五物汤加减对卵巢癌TP方案化疗引起神经毒性的防治效果. 陕西中医. 2016;4:396-7. Link

  • 徐成兴, 胡新民, 徐森华. 加味黄芪桂枝五物汤防治奥沙利铂致周围神经毒性的临床观察. 上海中医药杂志. 2017;1:53-63 Link

  • 苏碧莹, 黄海福. 黄芪桂枝五物汤联合温针灸治疗奥沙利铂神经毒性的临床观察. 中国中医药现代远程教育. 2018;18:81-3. Link

  • 吴婷婷, 金燕, 钟薏, 张士强, 李园, 杨蕴, et al. 黄芪桂枝五物汤联合逆针灸对恶性肿瘤患者化疗后周围神经毒性和免疫功能的影响. 山东医药. 2015;33:1-4. Link

  • 王泳, 杨建伟, 黄争荣, 陈乃杰, 王榕平, 赖义勤. 黄芪桂枝五物汤防治奥沙利铂所致急性神经毒性的临床观察. 广西中医药. 2018;5:20-4. Link

  • 于滨, 苏智祥, 袁媛, 吴敏慧.. 黄芪桂枝五物汤加减防治TP方案化疗引起神经毒性的疗效观察. 成都中医药大学学报. 2014;2:18-20. Link

  • 任明智, 王裕. 加味黄芪桂枝五物汤对化疗后周围神经病变的临床疗效研究. 中国医药指南. 2018;36:198-9. Link

  • Yuan L, Hui-juan G, Jin-chang H, Xiao-qin W. Clinical study of Jiawei Huangqi Guizhi Wuwu Decoction in preventing and treating peripheral neuro-sensory toxicity caused by oxaliplatin. Chinese Journal of Integrative Medicine. 2006;12(1):19–23. Link

  • 刘慧, 周之毅, 吴丽英, 王文海, 周荣耀, 黄建平, et al. 黄芪桂枝五物汤治疗奥沙利铂周围神经毒性的临床观察. 上海中医药杂志. 2011;3:44-7. Link

  • 徐先容. 黄芪桂枝五物汤加减对卵巢癌TP方案化疗引起神经毒性的防治效果. 陕西中医. 2016;4:396-7. Link

  • 徐成兴, 胡新民, 徐森华. 加味黄芪桂枝五物汤防治奥沙利铂致周围神经毒性的临床观察. 上海中医药杂志. 2017;1:53-63 Link

  • 苏碧莹, 黄海福. 黄芪桂枝五物汤联合温针灸治疗奥沙利铂神经毒性的临床观察. 中国中医药现代远程教育. 2018;18:81-3. Link

  • 吴婷婷, 金燕, 钟薏, 张士强, 李园, 杨蕴, et al. 黄芪桂枝五物汤联合逆针灸对恶性肿瘤患者化疗后周围神经毒性和免疫功能的影响. 山东医药. 2015;33:1-4. Link

  • 王泳, 杨建伟, 黄争荣, 陈乃杰, 王榕平, 赖义勤. 黄芪桂枝五物汤防治奥沙利铂所致急性神经毒性的临床观察. 广西中医药. 2018;5:20-4. Link

  • 于滨, 苏智祥, 袁媛, 吴敏慧.. 黄芪桂枝五物汤加减防治TP方案化疗引起神经毒性的疗效观察. 成都中医药大学学报. 2014;2:18-20. Link

  • 任明智, 王裕. 加味黄芪桂枝五物汤对化疗后周围神经病变的临床疗效研究. 中国医药指南. 2018;36:198-9. Link

항암화학요법 유발 말초신경병증 환자의 주 증상 예방을 위하여 일상관리 또는 무처치보다 한약 치료를 고려할 수 있다.

일상관리에는 대증지지요법과 재활치료가 포함된다. 항암제 유발 말초신경병증의 예방을 위한 한약치료처방은 황기계지오물탕, 우차신기환, 익기활혈탕 등을 고려할 수 있다. 복용방법은 일반적으로 항암화학요법 시작 전에 복용을 시작하여 하루2회-3회씩 8-24주간 복용한다.

C/Low

  • 许尤琪, 丁蓉. 益气活血对奥沙利铂神经毒性的干预作用. 中国中医药现代远程教育.2010;4:46-7. Link

  • 丁蓉, 霍介格, 汪悦. 当归四逆汤防治奥沙利铂周围神经毒性的临床观察. 南京中医药大学学报. 2014;5:432-3. Link

  • 张毅鹏. 加味阳和汤防治奥沙利铂周围神经毒性的临床观察. 中国现代医生. 2018;15:124-6. Link

  • 张炜炜. 中药预防奥沙利铂化疗相关的神经毒性反应临床分析. 光明中医. 2018;24:3676-8. Link

  • 张丽红, 庄志江, 张维真. 加味八珍汤对奥沙利铂神经毒性减毒增效研究. 成都中医药大学学报. 2015;2:52-4. Link

  • 任明智, 王裕. 加味黄芪桂枝五物汤对化疗后周围神经病变的临床疗效研究. 中国医药指南.2018;36:198-9. Link

  • 于滨, 苏智祥, 袁媛, 吴敏慧. 黄芪桂枝五物汤加减防治TP方案化疗引起神经毒性的疗效观察.成都中医药大学学报. 2014;2:18-20. Link

  • 王泳, 杨建伟, 黄争荣, 陈乃杰, 王榕平, 赖义勤. 黄芪桂枝五物汤防治奥沙利铂所致急性神经毒性的临床观察. 广西中医药. 2018;5:20-4. Link

  • 大鹏. 加味理中汤用于结直肠癌化疗致外周神经病变治疗中临床研究. 双足与保健.2017;15:172-98. Link

  • 吴婷婷, 金燕, 钟薏, et al. 黄芪桂枝五物汤联合逆针灸对恶性肿瘤患者化疗后周围神经毒性和免疫功能的影响. 山东医药. 2015;33:1-4. Link

  • 吴敏华, 陈旭烽, 周月芬, 张士强, 李园, 杨蕴, et al. 益气活血法与健脾补肾法预防奥沙利铂相关神经毒性. 中华中医药学刊. 2012;1:111-3. Link

  • 习隽丽, 石磊, 张昌欨, 沈克平. 中医健脾法配合FOLFOX化疗方案对结肠癌术后癌因性疲乏、Th1/ Th2免疫应答平衡和周围神经病变的影响观察. 中华中医药学刊. 2019;6:1503-5. Link

  • 苏碧莹, 黄海福. 黄芪桂枝五物汤联合温针灸治疗奥沙利铂神经毒性的临床观察. 中国中医药现代远程教育. 2018;18:81-3. Link

  • 徐成兴, 胡新民, 徐森华. 加味黄芪桂枝五物汤防治奥沙利铂致周围神经毒性的临床观察. 上海中医药杂志. 2017;1:53-63. Link

  • 徐先容. 黄芪桂枝五物汤加减对卵巢癌TP方案化疗引起神经毒性的防治效果. 陕西中医. 2016;4:396-7. Link

  • 范越, 厉天瑜, 张雯, 程悦蕾, 张怡, 李琦. 健脾解毒方防治大肠癌术后化疗相关周围神经病变的临床研究. 上海中医药杂志. 2018;10:49-53. Link

  • 白晶, 石永康. 通脉四逆汤加味治疗奥沙利铂所致周围神经毒性的临床观察. 中外医学研究. 2016;22:111-3. Link

  • 林岩, 许尤琪, 丁蓉. 中药复方对奥沙利铂神经毒性的干预作用观察. 中国癌症防治杂志. 2009;4:333-4. Link

  • 刘慧, 周之毅, 吴丽英, 王文海, 周荣耀, 黄建平, et al. 黄芪桂枝五物汤治疗奥沙利铂周围神经毒性的临床观察. 上海中医药杂志. 2011;3:44-7. Link

  • 童洪亮. 救生汤加味防治奥沙利铂外周神经毒性效果观察. 河南医学研究. 2016;4:613-5. Link

  • 呙清临, 张在翔, 罗显林, 乔普荣. 加味当归四逆汤防治草酸铂化疗致周围神经毒性的临床研究. 湖北中医杂志. 2016;5:4-6. Link

  • Nishioka M, Shimada M, Kurita N, Iwata T, Morimoto S, Yoshikawa K, et al. The Kampo medicine,
    Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen. International Journal of Clinical Oncology. 2011;16(4):322–7. Link

  • Motoo Y, Tomita Y, Fujita H. Prophylactic efficacy of ninjin’yoeito for oxaliplatin-induced cumulative
    peripheral neuropathy in patients with colorectal cancer receiving postoperative adjuvant chemotherapy:
    a randomized, open-label, phase 2 trial (HOPE-2). International Journal of Clinical Oncology. 2020;25(6):1123–9. Link

  • Yuan L, Hui-juan G, Jin-chang H, Xiao-qin W. Clinical study of Jiawei Huangqi Guizhi Wuwu Decoction in preventing and treating peripheral neuro-sensory toxicity caused by oxaliplatin. Chinese Journal of Integrative Medicine. 2006;12(1):19–23. Link

  • Cao B, Den W. Clinical observation of treatment with Yiqi Jianpi decoction combined with FOLFOX4 for the postoperation patients of colorectal cancer. The Chinese-German Journal of Clinical Oncology. 2012;11(10):605–8. Link

  • Abe H, Kawai Y, Mori T, Tomida K, Kubota Y, Umeda T, et al. The Kampo Medicine Goshajinkigan Prevents Neuropathy in Breast Cancer Patients Treated with Docetaxel. Asian Pacific Journal of Cancer Prevention. 2013;14(11):6351–6. Link

  • 孙一予, 贾英杰, 黄敏娜, 陈军. 补阳还五汤加减防治化疗后外周神经病变的临床观察. 光明中医. 2008;7:958-9. Link

  • 刘永华, 江锦红, 章俏雷, 金伟媚, 兰义芬, 周泽平, et al. “补肾活血”法预防硼替佐米治疗多发性骨髓瘤致周围神经病变的疗效观察. 中华全科医学. 2020;3:374-6. Link

  • 许尤琪, 丁蓉. 益气活血对奥沙利铂神经毒性的干预作用. 中国中医药现代远程教育.2010;4:46-7. Link

  • 丁蓉, 霍介格, 汪悦. 当归四逆汤防治奥沙利铂周围神经毒性的临床观察. 南京中医药大学学报. 2014;5:432-3. Link

  • 张毅鹏. 加味阳和汤防治奥沙利铂周围神经毒性的临床观察. 中国现代医生. 2018;15:124-6. Link

  • 张炜炜. 中药预防奥沙利铂化疗相关的神经毒性反应临床分析. 光明中医. 2018;24:3676-8. Link

  • 张丽红, 庄志江, 张维真. 加味八珍汤对奥沙利铂神经毒性减毒增效研究. 成都中医药大学学报. 2015;2:52-4. Link

  • 任明智, 王裕. 加味黄芪桂枝五物汤对化疗后周围神经病变的临床疗效研究. 中国医药指南.2018;36:198-9. Link

  • 于滨, 苏智祥, 袁媛, 吴敏慧. 黄芪桂枝五物汤加减防治TP方案化疗引起神经毒性的疗效观察.成都中医药大学学报. 2014;2:18-20. Link

  • 王泳, 杨建伟, 黄争荣, 陈乃杰, 王榕平, 赖义勤. 黄芪桂枝五物汤防治奥沙利铂所致急性神经毒性的临床观察. 广西中医药. 2018;5:20-4. Link

  • 大鹏. 加味理中汤用于结直肠癌化疗致外周神经病变治疗中临床研究. 双足与保健.2017;15:172-98. Link

  • 吴婷婷, 金燕, 钟薏, et al. 黄芪桂枝五物汤联合逆针灸对恶性肿瘤患者化疗后周围神经毒性和免疫功能的影响. 山东医药. 2015;33:1-4. Link

  • 吴敏华, 陈旭烽, 周月芬, 张士强, 李园, 杨蕴, et al. 益气活血法与健脾补肾法预防奥沙利铂相关神经毒性. 中华中医药学刊. 2012;1:111-3. Link

  • 习隽丽, 石磊, 张昌欨, 沈克平. 中医健脾法配合FOLFOX化疗方案对结肠癌术后癌因性疲乏、Th1/ Th2免疫应答平衡和周围神经病变的影响观察. 中华中医药学刊. 2019;6:1503-5. Link

  • 苏碧莹, 黄海福. 黄芪桂枝五物汤联合温针灸治疗奥沙利铂神经毒性的临床观察. 中国中医药现代远程教育. 2018;18:81-3. Link

  • 徐成兴, 胡新民, 徐森华. 加味黄芪桂枝五物汤防治奥沙利铂致周围神经毒性的临床观察. 上海中医药杂志. 2017;1:53-63. Link

  • 徐先容. 黄芪桂枝五物汤加减对卵巢癌TP方案化疗引起神经毒性的防治效果. 陕西中医. 2016;4:396-7. Link

  • 范越, 厉天瑜, 张雯, 程悦蕾, 张怡, 李琦. 健脾解毒方防治大肠癌术后化疗相关周围神经病变的临床研究. 上海中医药杂志. 2018;10:49-53. Link

  • 白晶, 石永康. 通脉四逆汤加味治疗奥沙利铂所致周围神经毒性的临床观察. 中外医学研究. 2016;22:111-3. Link

  • 林岩, 许尤琪, 丁蓉. 中药复方对奥沙利铂神经毒性的干预作用观察. 中国癌症防治杂志. 2009;4:333-4. Link

  • 刘慧, 周之毅, 吴丽英, 王文海, 周荣耀, 黄建平, et al. 黄芪桂枝五物汤治疗奥沙利铂周围神经毒性的临床观察. 上海中医药杂志. 2011;3:44-7. Link

  • 童洪亮. 救生汤加味防治奥沙利铂外周神经毒性效果观察. 河南医学研究. 2016;4:613-5. Link

  • 呙清临, 张在翔, 罗显林, 乔普荣. 加味当归四逆汤防治草酸铂化疗致周围神经毒性的临床研究. 湖北中医杂志. 2016;5:4-6. Link

  • Nishioka M, Shimada M, Kurita N, Iwata T, Morimoto S, Yoshikawa K, et al. The Kampo medicine,
    Goshajinkigan, prevents neuropathy in patients treated by FOLFOX regimen. International Journal of Clinical Oncology. 2011;16(4):322–7. Link

  • Motoo Y, Tomita Y, Fujita H. Prophylactic efficacy of ninjin’yoeito for oxaliplatin-induced cumulative
    peripheral neuropathy in patients with colorectal cancer receiving postoperative adjuvant chemotherapy:
    a randomized, open-label, phase 2 trial (HOPE-2). International Journal of Clinical Oncology. 2020;25(6):1123–9. Link

  • Yuan L, Hui-juan G, Jin-chang H, Xiao-qin W. Clinical study of Jiawei Huangqi Guizhi Wuwu Decoction in preventing and treating peripheral neuro-sensory toxicity caused by oxaliplatin. Chinese Journal of Integrative Medicine. 2006;12(1):19–23. Link

  • Cao B, Den W. Clinical observation of treatment with Yiqi Jianpi decoction combined with FOLFOX4 for the postoperation patients of colorectal cancer. The Chinese-German Journal of Clinical Oncology. 2012;11(10):605–8. Link

  • Abe H, Kawai Y, Mori T, Tomida K, Kubota Y, Umeda T, et al. The Kampo Medicine Goshajinkigan Prevents Neuropathy in Breast Cancer Patients Treated with Docetaxel. Asian Pacific Journal of Cancer Prevention. 2013;14(11):6351–6. Link

  • 孙一予, 贾英杰, 黄敏娜, 陈军. 补阳还五汤加减防治化疗后外周神经病变的临床观察. 光明中医. 2008;7:958-9. Link

  • 刘永华, 江锦红, 章俏雷, 金伟媚, 兰义芬, 周泽平, et al. “补肾活血”法预防硼替佐米治疗多发性骨髓瘤致周围神经病变的疗效观察. 中华全科医学. 2020;3:374-6. Link

항암화학요법 유발 말초신경병증 환자의 주 증상 예방을 위하여 우차신기환을 고려할 수 있다.

복용방법은 일반적으로 항암화학요법 시작 전에 복용을 시작하여 하루2회-3회씩 8주-24주간 복용한다.

C/Very Low

  • Oki E, Emi Y, Kojima H, Higashijima J, Kato T, Miyake Y, et al. Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy (GENIUS trial): a placebo-controlled, double-blind, randomized phase III study. International Journal of Clinical Oncology.2015;20(4):767–75. Link

  • Kono T, Hata T, Morita S, Munemoto Y, Matsui T, Kojima H, et al. Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy. Cancer Chemotherapy and Pharmacology. 2013;72(6):1283–90. Link

  • Oki E, Emi Y, Kojima H, Higashijima J, Kato T, Miyake Y, et al. Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy (GENIUS trial): a placebo-controlled, double-blind, randomized phase III study. International Journal of Clinical Oncology.2015;20(4):767–75. Link

  • Kono T, Hata T, Morita S, Munemoto Y, Matsui T, Kojima H, et al. Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy. Cancer Chemotherapy and Pharmacology. 2013;72(6):1283–90. Link

항암화학요법 유발 말초신경병증 환자의 주 증상 예방을 위하여 한약 치료를 고려할 수 있다.

복용방법은 일반적으로 항암화학요법 시작 전에 복용을 시작하여 하루 2회-3회씩 8주-24주간 복용한다.

C/Very Low

  • Liu Y, Zhu G, Han L, Liu J, Ma T, Yu H. Clinical Study on the Prevention of Oxaliplatin-Induced Neurotoxicity with Guilongtongluofang: Results of a Randomized, Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2013;2013:1–7. Link

  • Oki E, Emi Y, Kojima H, Higashijima J, Kato T, Miyake Y, et al. Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy (GENIUS trial): a placebo-controlled, double-blind, randomized phase III study. International Journal of Clinical Oncology. 2015;20(4):767–75. Link

  • Kono T, Hata T, Morita S, Munemoto Y, Matsui T, Kojima H, et al. Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy. Cancer Chemotherapy and Pharmacology. 2013;72(6):1283–90. Link

  • Liu Y, Zhu G, Han L, Liu J, Ma T, Yu H. Clinical Study on the Prevention of Oxaliplatin-Induced Neurotoxicity with Guilongtongluofang: Results of a Randomized, Double-Blind, Placebo-Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2013;2013:1–7. Link

  • Oki E, Emi Y, Kojima H, Higashijima J, Kato T, Miyake Y, et al. Preventive effect of Goshajinkigan on peripheral neurotoxicity of FOLFOX therapy (GENIUS trial): a placebo-controlled, double-blind, randomized phase III study. International Journal of Clinical Oncology. 2015;20(4):767–75. Link

  • Kono T, Hata T, Morita S, Munemoto Y, Matsui T, Kojima H, et al. Goshajinkigan oxaliplatin neurotoxicity evaluation (GONE): a phase 2, multicenter, randomized, double-blind, placebo-controlled trial of goshajinkigan to prevent oxaliplatin-induced neuropathy. Cancer Chemotherapy and Pharmacology. 2013;72(6):1283–90. Link

항암화학요법 유발 말초신경병증 환자의 주 증상 개선을 위하여 일상관리보다 침치료 및 일상관리의 병행을 고려해야 한다.

일상관리에는 대증지지요법과 재활치료가 포함된다. 혈자리로는 태충(LR3), 족삼리(ST36), 삼음교(SP6), 태백(SP3), 합곡(LI4), 태계(KI3), 팔풍, 팔사를 고려할 수 있다. 치료기간은 보통 주2-3회, 4주-12주 치료한다.

B/Low

  • Molassiotis A, Suen LK, Cheng HL, Mok TS, Lee SC, Wang CH, et al. A Randomized Assessor-
    Blinded Wait-List-Controlled Trial to Assess the Effectiveness of Acupuncture in the Management
    of Chemotherapy-Induced Peripheral Neuropathy. Integrative Cancer Therapies. 2019;18:153473541983650. Link

  • D’Alessandro EG, Nagy DRN, de Brito CMM, Almeida EPM, Battistella LR, Cecatto RB. Acupuncture for chemotherapy-induced peripheral neuropathy: a randomised controlled pilot study. BMJ Supportive & Palliative Care 2019;0:1–9. Link

  • Han X, Wang L, Shi H, Zheng G, He J, Wu W, et al. Acupuncture combined with methylcobalamin for the treatment of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma. BMC Cancer. 2016;17(1):40. Link

  • Molassiotis A, Suen LK, Cheng HL, Mok TS, Lee SC, Wang CH, et al. A Randomized Assessor-
    Blinded Wait-List-Controlled Trial to Assess the Effectiveness of Acupuncture in the Management
    of Chemotherapy-Induced Peripheral Neuropathy. Integrative Cancer Therapies. 2019;18:153473541983650. Link

  • D’Alessandro EG, Nagy DRN, de Brito CMM, Almeida EPM, Battistella LR, Cecatto RB. Acupuncture for chemotherapy-induced peripheral neuropathy: a randomised controlled pilot study. BMJ Supportive & Palliative Care 2019;0:1–9. Link

  • Han X, Wang L, Shi H, Zheng G, He J, Wu W, et al. Acupuncture combined with methylcobalamin for the treatment of chemotherapy-induced peripheral neuropathy in patients with multiple myeloma. BMC Cancer. 2016;17(1):40. Link

항암화학요법 유발 오심구토 환자의 주 증상 개선을 위하여 항구토제보다 침 치료 및 항구토제의 병행을 고려해야 한다.

혈자리로는 내관(PC6), 족삼리(ST36), 중완(CV12), 기해(CV6), 태충(LR3), 공손(SP4)을 고려할 수 있다. 치료기간은 보통 매일, 3일-7일 치료한다.

B/Low

  • Shen J, Wenger N, Glaspy J, Hays RD, Albert PS, Choi C, et al. Electroacupuncture for Control
    of Myeloablative Chemotherapy–Induced Emesis. JAMA. 2000;284(21):2755. Link

  • McKeon C, Smith CA, Gibbons K, Hardy J, Haugstetter C, Anderson H. Ea versus Sham Acupuncture
    and no Acupuncture for the Control of Acute and Delayed Chemotherapy-Induced
    Nausea and Vomiting: A Pilot Study. Acupuncture in Medicine. 2015;33(4):277–83. Link

  • Yang Y, Zhang Y, Jing NC, Lu Y, Xiao HY, Xu GL, et al. Electroacupuncture at Zusanli (ST 36) for treatment of nausea and vomiting caused by the chemotherapy of the malignant tumor: a multicentral randomized controlled trial. Zhongguo zhen jiu= Chinese acupuncture & moxibustion. 2009;29(12):955-8. Link

  • 朱伟坚, 徐妍, 周静, 珠李薇, 王茵萍. 电针耳迷走神经防治化疗后恶心呕吐的疗效观察. 山东中医杂志. 2016;5:415-9. Link

  • 黄克江, 宋祥忠, 王瑞珩. 电针预处理治疗乳癌术后化疗引起迟发性呕吐的临床病例观察. 针灸临床杂志. 2016;7:46-8. Link

  • 张青, 王笑民, 胡凤山, 赵文硕. 针刺特定穴位防治肿瘤患者化疗呕吐的临床观察. 中医杂志. 2006;3:209-10. Link

  • 武百强, 陈福春, 潘琦, 薛洁皓, 鲍军. 针刺足三里防治肺癌化疗呕吐的临床研究. 中华中医药学刊. 2011;2:406-8. Link

  • 赖米林, 刘丹. 薄氏腹针治疗乳腺癌化疗后恶心呕吐的疗效观察. 数理医药学杂志. 2015;9: 1295-6. Link

  • 秦均匀. 腹针联合昂丹司琼注射液治疗恶性骨肿瘤化疗后呕吐23例. Traditional Chinese Medicinal Research. 2018;11:52-3. Link

  • 郑蔚. 内关穴皮内针埋针对乳腺癌病人化疗恶心、呕吐的影响. 护理研究. 2012;28:2641-2. Link

  • 唐倩, 廖大忠, 李修元. 皮内针联合西药治疗肿瘤化疗后恶心呕吐的临床研究. 中医药学报. 2018;5:54-7. Link

  • 张旭岗. 皮内针联合西药治疗肿瘤化疗后恶心呕吐效果. 中国卫生标准管理. 2019;12:89-91. Link

  • 蔡鹄, 龚黎燕, 张波, 方晓, 刘洁. 穴位揿针联合西药防治小细胞肺癌EP方案化疗相关性恶心呕吐临床观察. 上海针灸杂志. 2019;4:355-8. Link

  • Shen J, Wenger N, Glaspy J, Hays RD, Albert PS, Choi C, et al. Electroacupuncture for Control
    of Myeloablative Chemotherapy–Induced Emesis. JAMA. 2000;284(21):2755. Link

  • McKeon C, Smith CA, Gibbons K, Hardy J, Haugstetter C, Anderson H. Ea versus Sham Acupuncture
    and no Acupuncture for the Control of Acute and Delayed Chemotherapy-Induced
    Nausea and Vomiting: A Pilot Study. Acupuncture in Medicine. 2015;33(4):277–83. Link

  • Yang Y, Zhang Y, Jing NC, Lu Y, Xiao HY, Xu GL, et al. Electroacupuncture at Zusanli (ST 36) for treatment of nausea and vomiting caused by the chemotherapy of the malignant tumor: a multicentral randomized controlled trial. Zhongguo zhen jiu= Chinese acupuncture & moxibustion. 2009;29(12):955-8. Link

  • 朱伟坚, 徐妍, 周静, 珠李薇, 王茵萍. 电针耳迷走神经防治化疗后恶心呕吐的疗效观察. 山东中医杂志. 2016;5:415-9. Link

  • 黄克江, 宋祥忠, 王瑞珩. 电针预处理治疗乳癌术后化疗引起迟发性呕吐的临床病例观察. 针灸临床杂志. 2016;7:46-8. Link

  • 张青, 王笑民, 胡凤山, 赵文硕. 针刺特定穴位防治肿瘤患者化疗呕吐的临床观察. 中医杂志. 2006;3:209-10. Link

  • 武百强, 陈福春, 潘琦, 薛洁皓, 鲍军. 针刺足三里防治肺癌化疗呕吐的临床研究. 中华中医药学刊. 2011;2:406-8. Link

  • 赖米林, 刘丹. 薄氏腹针治疗乳腺癌化疗后恶心呕吐的疗效观察. 数理医药学杂志. 2015;9: 1295-6. Link

  • 秦均匀. 腹针联合昂丹司琼注射液治疗恶性骨肿瘤化疗后呕吐23例. Traditional Chinese Medicinal Research. 2018;11:52-3. Link

  • 郑蔚. 内关穴皮内针埋针对乳腺癌病人化疗恶心、呕吐的影响. 护理研究. 2012;28:2641-2. Link

  • 唐倩, 廖大忠, 李修元. 皮内针联合西药治疗肿瘤化疗后恶心呕吐的临床研究. 中医药学报. 2018;5:54-7. Link

  • 张旭岗. 皮内针联合西药治疗肿瘤化疗后恶心呕吐效果. 中国卫生标准管理. 2019;12:89-91. Link

  • 蔡鹄, 龚黎燕, 张波, 方晓, 刘洁. 穴位揿针联合西药防治小细胞肺癌EP方案化疗相关性恶心呕吐临床观察. 上海针灸杂志. 2019;4:355-8. Link

항암화학요법 유발 오심구토 환자의 주 증상 개선을 위하여 침 치료를 고려해야 한다.

혈자리로는 내관(PC6), 족삼리(ST36), 중완(CV12), 기해(CV6), 태충(LR3), 공손(SP4)을 고려할 수 있다. 치료기간은 보통 매일, 3일-7일 치료한다.

B/Moderate

  • Shen J, Wenger N, Glaspy J, Hays RD, Albert PS, Choi C, et al. Electroacupuncture for Control of Myeloablative Chemotherapy–Induced Emesis. JAMA. 2000;284(21):2755. Link

  • 何佩珊, 潘国凤, 王笑民, 杨国旺, 杨公博, 李琦玮, et al. “老十针”防治乳腺癌化疗相关恶心呕吐的前瞻性随机对照研究. 中华中医药杂志. 2017;6:2805-7. Link

  • Zhang X, Fan Y. Effects of electroacupuncture on chemotherapy-induced nausea and vomiting and its mechanism. Chinese acupuncture & moxibustion. 2014;34(11):1061-4. Link

  • Shen J, Wenger N, Glaspy J, Hays RD, Albert PS, Choi C, et al. Electroacupuncture for Control of Myeloablative Chemotherapy–Induced Emesis. JAMA. 2000;284(21):2755. Link

  • 何佩珊, 潘国凤, 王笑民, 杨国旺, 杨公博, 李琦玮, et al. “老十针”防治乳腺癌化疗相关恶心呕吐的前瞻性随机对照研究. 中华中医药杂志. 2017;6:2805-7. Link

  • Zhang X, Fan Y. Effects of electroacupuncture on chemotherapy-induced nausea and vomiting and its mechanism. Chinese acupuncture & moxibustion. 2014;34(11):1061-4. Link

성인 암 생존자의 수면의 질 개선을 위하여 무처치보다 마음챙김에 기반한 스트레 스 감소 프로그램(MBSR)을 시행할 것을 고려해야 한다.

MBSR은 매 회기 2시간, 8회기가 기본이지만 임상 상황에 따라 1시간으로 단축하여 실시할 수 있다. 8회기의 정규 프로그램 외에도 환자가 집에서 매일 명상훈련을 복습할 수 있도록 지도하는 것이 중요하다.

B/Low

  • Lengacher CA, Reich RR, Paterson CL, Jim HS, Ramesar S, Alinat CB, et al. The effects of mindfulness-based stress reduction on objective and subjective sleep parameters in women with breast cancer: a randomized controlled trial. Psycho-Oncology. 2014;24(4):424–32. Link

  • Zhang H, Li Y, Li M, Chen X. A randomized controlled trial of mindfulness-based stress reduction for insomnia secondary to cervical cancer: Sleep effects. Applied Nursing Research. 2019;48:52–7. Link

  • Lengacher CA, Reich RR, Post-White J, Moscoso M, Shelton MM, Barta M, et al. Mindfulness based stress reduction in post-treatment breast cancer patients: an examination of symptoms and symptom clusters. Journal of Behavioral Medicine. 2012;35(1):86–94. Link

  • Andersen SR, Würtzen H, Steding-Jessen M, Christensen J, Andersen KK, Flyger H, et al. Effect
    of mindfulness-based stress reduction on sleep quality: Results of a randomized trial among Danish
    breast cancer patients. Acta Oncologica. 2013;52(2):336–44. Link

  • Johns SA, Brown LF, Beck-Coon K, Monahan PO, Tong Y, Kroenke K. Randomized controlled pilot study of mindfulness-based stress reduction for persistently fatigued cancer survivors. Psycho-Oncology. 2015;24(8):885–93. Link

  • Blaes A, Fenner D, Bachanova V, Torkelson C, Geller M, Haddad T, et al. Mindfulness-based cancer recovery in survivors recovering from chemotherapy and radiation. The Journal of Community and Supportive Oncology. 2016;:351–8. Link

  • Reich RR, Lengacher CA, Alinat CB, Kip KE, Paterson C, Ramesar S, et al. Mindfulness-Based Stress Reduction in Post-treatment Breast Cancer Patients: Immediate and Sustained Effects Across Multiple Symptom Clusters. Journal of Pain and Symptom Management. 2017;53(1):85–95. Link

  • Lengacher CA, Reich RR, Paterson CL, Jim HS, Ramesar S, Alinat CB, et al. The effects of mindfulness-based stress reduction on objective and subjective sleep parameters in women with breast cancer: a randomized controlled trial. Psycho-Oncology. 2014;24(4):424–32. Link

  • Zhang H, Li Y, Li M, Chen X. A randomized controlled trial of mindfulness-based stress reduction for insomnia secondary to cervical cancer: Sleep effects. Applied Nursing Research. 2019;48:52–7. Link

  • Lengacher CA, Reich RR, Post-White J, Moscoso M, Shelton MM, Barta M, et al. Mindfulness based stress reduction in post-treatment breast cancer patients: an examination of symptoms and symptom clusters. Journal of Behavioral Medicine. 2012;35(1):86–94. Link

  • Andersen SR, Würtzen H, Steding-Jessen M, Christensen J, Andersen KK, Flyger H, et al. Effect
    of mindfulness-based stress reduction on sleep quality: Results of a randomized trial among Danish
    breast cancer patients. Acta Oncologica. 2013;52(2):336–44. Link

  • Johns SA, Brown LF, Beck-Coon K, Monahan PO, Tong Y, Kroenke K. Randomized controlled pilot study of mindfulness-based stress reduction for persistently fatigued cancer survivors. Psycho-Oncology. 2015;24(8):885–93. Link

  • Blaes A, Fenner D, Bachanova V, Torkelson C, Geller M, Haddad T, et al. Mindfulness-based cancer recovery in survivors recovering from chemotherapy and radiation. The Journal of Community and Supportive Oncology. 2016;:351–8. Link

  • Reich RR, Lengacher CA, Alinat CB, Kip KE, Paterson C, Ramesar S, et al. Mindfulness-Based Stress Reduction in Post-treatment Breast Cancer Patients: Immediate and Sustained Effects Across Multiple Symptom Clusters. Journal of Pain and Symptom Management. 2017;53(1):85–95. Link

암성 식욕부진 환자의 주 증상 개선을 위하여 일상관리보다 육군자탕 및 일상관리 의 병행을 고려해야 한다.

암환자의 식욕부진을 개선하기 위해 대증치료, 항구토제, 영양상담 등의 일상관리와 육군자탕의 병행을 고려할 수 있다. 육군자탕의 가감으로 향부자, 사인을 가한 향사육군자탕과 지실, 후박을 가한 지박육군자탕으로 가감할 수 있다. 치료기간은 보통 3주-8주 치료한다.

B/Low

  • Ohno T, Yanai, Ando, Toyomasu, Ogawa, Morita, et al. Rikkunshito, a traditional Japanese medicine,
    suppresses cisplatin-induced anorexia in humans. Clinical and Experimental Gastroenterology. 2011;:291. Link

  • Hamai Y, Yoshiya T, Hihara J, Emi M, Furukawa T, Yamakita I, et al. Traditional Japanese herbal
    medicine rikkunshito increases food intake and plasma acylated ghrelin levels in patients with esophageal cancer treated by cisplatin-based chemotherapy. Journal of Thoracic Disease. 2019;11(6):2470–8. Link

  • Ohnishi S, Watari H, Kanno M, Ohba Y, Takeuchi S, Miyaji T, et al. Additive effect of rikkunshito,
    an herbal medicine, on chemotherapy-induced nausea, vomiting, and anorexia in uterine cervical or corpus cancer patients treated with cisplatin and paclitaxel: results of a randomized phase II study (JORTC KMP-02). Journal of Gynecologic Oncology. 2017;28(5). Link

  • Yoshiya T, Mimae T, Ito M, Sasada S, Tsutani Y, Satoh K, et al. Prospective, randomized, crossover pilot study of the effects of Rikkunshito, a Japanese traditional herbal medicine, on anorexia and plasma-acylated ghrelin levels in lung cancer patients undergoing cisplatin-based chemotherapy. Investigational New Drugs. 2020;38(2):485–92. Link

  • Ko MH, Song SY, Ha SJ, Lee JY, Yoon SW, Park JH, Park SJ, Yoo HS. Efficacy and Safety of Yukgunja-Tang for Patients with Cancer-related Anorexia: A Randomized, Controlled Trial, Pilot Study. Integr Cancer Ther. 2021;20:15347354211019107. Link

  • Ohno T, Yanai, Ando, Toyomasu, Ogawa, Morita, et al. Rikkunshito, a traditional Japanese medicine,
    suppresses cisplatin-induced anorexia in humans. Clinical and Experimental Gastroenterology. 2011;:291. Link

  • Hamai Y, Yoshiya T, Hihara J, Emi M, Furukawa T, Yamakita I, et al. Traditional Japanese herbal
    medicine rikkunshito increases food intake and plasma acylated ghrelin levels in patients with esophageal cancer treated by cisplatin-based chemotherapy. Journal of Thoracic Disease. 2019;11(6):2470–8. Link

  • Ohnishi S, Watari H, Kanno M, Ohba Y, Takeuchi S, Miyaji T, et al. Additive effect of rikkunshito,
    an herbal medicine, on chemotherapy-induced nausea, vomiting, and anorexia in uterine cervical or corpus cancer patients treated with cisplatin and paclitaxel: results of a randomized phase II study (JORTC KMP-02). Journal of Gynecologic Oncology. 2017;28(5). Link

  • Yoshiya T, Mimae T, Ito M, Sasada S, Tsutani Y, Satoh K, et al. Prospective, randomized, crossover pilot study of the effects of Rikkunshito, a Japanese traditional herbal medicine, on anorexia and plasma-acylated ghrelin levels in lung cancer patients undergoing cisplatin-based chemotherapy. Investigational New Drugs. 2020;38(2):485–92. Link

  • Ko MH, Song SY, Ha SJ, Lee JY, Yoon SW, Park JH, Park SJ, Yoo HS. Efficacy and Safety of Yukgunja-Tang for Patients with Cancer-related Anorexia: A Randomized, Controlled Trial, Pilot Study. Integr Cancer Ther. 2021;20:15347354211019107. Link

암성 식욕부진 환자의 주 증상 개선을 위하여 식욕촉진제보다 한약 치료를 고려할 수 있다.

암환자의 식욕부진은 다학제적 접근이 필요하다. 치료로는 육군자탕, 향사육군자탕, 삼출건비탕, 개위진식탕 등을 고려할 수 있다. 치료기간은 보통 3주-8주 치료한다.

C/Low

  • 李佳汝, 王海威, 贾玫, 李潇, 杜怀棠. 加味枳术颗粒改善肿瘤患者癌性厌食的临床观察. 中国临床医生. 2014;9:24-6. Link

  • 易琰斐. 开胃进食汤治疗恶性肿瘤相关性厌食临床疗效分析. 亚太传统医药. 2016;22:138-9. Link

  • 王宜宗, 祝明池, 赵文, 张秀凤. 薯蓣丸治疗肿瘤相关性厌食疗效观察. 中医药临床杂志. 2013;10:850-2. Link

  • 王鹂, 邹玺, 刘沈林. 香砂六君汤加减联合甲羟孕酮治疗肿瘤食欲不振—恶病质综合征临床研究. 中国中西医结合杂志. 2018;8:927-31. Link

  • 蔡红兵, 罗荣城, 杨传标, 潘春华, 左强, 王月刚. 补中益气汤治疗癌症食欲不振-恶病质综合征30例疗效观察. 新中醫. 2003;3:25-6. Link

  • 崔艺馨, 张印, 任芳, 王海明, 冯宇, 李绍旦. 开胃进食汤治疗恶性肿瘤相关性厌食临床研究. 北京中医药. 2015;5:353-5. Link

  • 陈捷. 枳朴六君子汤加味治疗癌症食欲不振-恶病质综合征56例. 陕西中医. 2007;9:1182-3. Link

  • 黄景彬, 林清, 陈雁秋, 陈洁. 香砂六君子汤加味治疗化疗后厌食症. 中医临床研究. 2015;8:64-6. Link

  • 李佳汝, 王海威, 贾玫, 李潇, 杜怀棠. 加味枳术颗粒改善肿瘤患者癌性厌食的临床观察. 中国临床医生. 2014;9:24-6. Link

  • 易琰斐. 开胃进食汤治疗恶性肿瘤相关性厌食临床疗效分析. 亚太传统医药. 2016;22:138-9. Link

  • 王宜宗, 祝明池, 赵文, 张秀凤. 薯蓣丸治疗肿瘤相关性厌食疗效观察. 中医药临床杂志. 2013;10:850-2. Link

  • 王鹂, 邹玺, 刘沈林. 香砂六君汤加减联合甲羟孕酮治疗肿瘤食欲不振—恶病质综合征临床研究. 中国中西医结合杂志. 2018;8:927-31. Link

  • 蔡红兵, 罗荣城, 杨传标, 潘春华, 左强, 王月刚. 补中益气汤治疗癌症食欲不振-恶病质综合征30例疗效观察. 新中醫. 2003;3:25-6. Link

  • 崔艺馨, 张印, 任芳, 王海明, 冯宇, 李绍旦. 开胃进食汤治疗恶性肿瘤相关性厌食临床研究. 北京中医药. 2015;5:353-5. Link

  • 陈捷. 枳朴六君子汤加味治疗癌症食欲不振-恶病质综合征56例. 陕西中医. 2007;9:1182-3. Link

  • 黄景彬, 林清, 陈雁秋, 陈洁. 香砂六君子汤加味治疗化疗后厌食症. 中医临床研究. 2015;8:64-6. Link

암성 식욕부진 환자의 주 증상 개선을 위하여 일상관리 또는 무처치보다 한약 치료 를 고려해야 한다.

암환자의 식욕부진은 악액질 및 암치료 부작용 등과 관련되어 있을 수 있으므로 다학제적 접근이 필요하다. 일상관리에는 영양지지요법 및 대증 치료가 포함된다. 암성 식욕부진의 치료로는 육군자탕, 향사육군자탕, 삼출건비탕, 개위진식탕 등을 고려할 수 있다. 치료기간은 보통 3주-8주 치료한다.

B/Moderate

  • 何依群, 姜鹤群, 王少龙, 杨晓琳. 八珍冲剂治疗化疗后食欲减退的临床观察. 海南醫學. 2007;11:87. Link

  • 严伟华, 黄进林, 陈洁. 香砂枳术煎加味改善肿瘤相关性厌食的临床观察. 中国当代医药. 2012;32:120-1. Link

  • 陈捷. 枳朴六君子汤加味治疗癌症食欲不振-恶病质综合征56例. 陕西中医. 2007;9:1182-3. Link

  • 蔡红兵, 罗荣城, 杨 传标, 潘春华, 左强, 王月刚. 补中益气汤治疗癌症食欲不振-恶病质综合征30例疗效观察. 新中醫. 2003;3:25-6. Link

  • 邓国忠. 香砂二芽开胃汤治疗癌症患者放疗中食欲不振. 四川中醫. 1997;9:32. Link

  • 何依群, 姜鹤群, 王少龙, 杨晓琳. 八珍冲剂治疗化疗后食欲减退的临床观察. 海南醫學. 2007;11:87. Link

  • 严伟华, 黄进林, 陈洁. 香砂枳术煎加味改善肿瘤相关性厌食的临床观察. 中国当代医药. 2012;32:120-1. Link

  • 陈捷. 枳朴六君子汤加味治疗癌症食欲不振-恶病质综合征56例. 陕西中医. 2007;9:1182-3. Link

  • 蔡红兵, 罗荣城, 杨 传标, 潘春华, 左强, 王月刚. 补中益气汤治疗癌症食欲不振-恶病质综合征30例疗效观察. 新中醫. 2003;3:25-6. Link

  • 邓国忠. 香砂二芽开胃汤治疗癌症患者放疗中食欲不振. 四川中醫. 1997;9:32. Link

암성 통증 환자의 주 증상 개선을 위하여 진통제보다 뜸 치료 및 진통제의 병행을 고려할 수 있다.

암성 통증은 다학제적 진단 및 치료의 병행을 고려해야 하며 종양의 직접적 원인으로 발생할 가능성을 항상 염두에 두어야 한다. 뜸 치료로 인한 화상을 주의해야 한다. 혈자리로는 아시혈, 배수혈, 족삼리(ST36), 합곡(LI4), 태충(LR3), 관원(CV4), 중완(CV12)을 고려할 수 있다. 치료기간은 보통 주2회-5회, 3주-8주 치료한다.

C/Low

  • 杨俊. 镇痛灸治疗恶性肿瘤轻中度疼痛的疗效观察. 内蒙古中医药. 2015:34(9):49. Link

  • 李玲, 高翠霞, 何炜, 马桂霞, 王炜炜, 司慧彬, et al. 温阳艾灸法联合三阶梯止痛法对癌痛患者止痛效果和生活质量的影响. 中医硏究. 2016;29(9):48-50. Link

  • 邹蜜. 艾灸对晚期胃癌患者癌性疼痛缓解及生命质量的影响. 医疗装备. 2017;30(23):171-2. Link

  • 逄艳, 张芳. 脐灸联合三阶梯止痛法治疗虚寒型癌痛临床观察. 光明中医. 2019;34(22)3457-9. Link

  • 杨俊. 镇痛灸治疗恶性肿瘤轻中度疼痛的疗效观察. 内蒙古中医药. 2015:34(9):49. Link

  • 李玲, 高翠霞, 何炜, 马桂霞, 王炜炜, 司慧彬, et al. 温阳艾灸法联合三阶梯止痛法对癌痛患者止痛效果和生活质量的影响. 中医硏究. 2016;29(9):48-50. Link

  • 邹蜜. 艾灸对晚期胃癌患者癌性疼痛缓解及生命质量的影响. 医疗装备. 2017;30(23):171-2. Link

  • 逄艳, 张芳. 脐灸联合三阶梯止痛法治疗虚寒型癌痛临床观察. 光明中医. 2019;34(22)3457-9. Link

암성 통증 환자의 주 증상 개선을 위하여 진통제보다 봉독침 치료 및 진통제의 병행 을 고려할 수 있다.

암성 통증은 다학제적 진단 및 치료의 병행을 고려해야 하며 종양의 직접적 원인으로 발생할 가능성을 항상 염두에 두어야 한다. 봉독침 치료를 시행하기 전에 봉독 알러지 테스트를 하여 알러지 반응이 없을 때 봉독침 치료를 시행한다. 혈자리로는 아시혈, 배수혈, 족삼리(ST36), 삼음교(SP6)를 고려할 수 있다. 치료기간은 보통 주2회-3회, 2주-4주 치료한다

C/Low

  • 安香珍. 蜂针对肺癌合并癌性疼痛患者的疗效观察. 蜜蜂杂志. 2019;8:17-20. Link

  • 彭辉, 张志芳. 蜂针联合三阶梯止痛疗法治疗癌痛的临床观察. 湖南中医药大学学报. 2010;9:222-5. Link

  • 彭莉莉. 蜂针疗法治疗癌痛30例临床观察. 新中医. 2014;12:177-8. Link

  • 安香珍. 蜂针对肺癌合并癌性疼痛患者的疗效观察. 蜜蜂杂志. 2019;8:17-20. Link

  • 彭辉, 张志芳. 蜂针联合三阶梯止痛疗法治疗癌痛的临床观察. 湖南中医药大学学报. 2010;9:222-5. Link

  • 彭莉莉. 蜂针疗法治疗癌痛30例临床观察. 新中医. 2014;12:177-8. Link

암성 통증 환자의 주 증상 개선을 위하여 진통제보다 침 치료 및 진통제의 병행을 고려해야 한다.

암성 통증은 다학제적 진단 및 치료의 병행을 고려해야 하며 종양의 직접적 원인으로 발생할 가능성을 항상 염두에 두어야 한다. 혈자리로는 아시혈, 배수혈, 족삼리(ST36), 합곡(LI4), 태충(LR3), 관원(CV4), 중완(CV12)을 고려할 수 있다. 치료기간은 보통 주2회-5회, 3주-8주 치료한다.

B/Moderate

  • Chen ZJ, Guo YP, Wu ZC. Observation on the therapeutic effect of acupuncture at pain points
    on cancer pain. Zhongguo Zhen Jiu. 2008;28(4):251-3. Link

  • 邓懿, 硫酸吗啡控释片联合针刺改善老年癌性疼痛患者生存质量的效果. 现代中西医结合杂志, 2015;6:606-8. Link

  • Ding QG. Clinical study of acupuncture at Mingmen and Guanyuan acupoints combined with analgesic on the treatment of lumbar spinal metastatic carcinoma pains. Chinese medicine modern distance education of china [zhong guo zhong yi yao xian dai yuan cheng jiao yu]. 2015;13(7):65-6. Link

  • 江彬, 陈峰, 邓山, 杜慧静. 针刺太冲合谷治疗癌痛25例. 浙江中医杂志. 2016:4:270. Link

  • Li DH, Sun CX, Fan HF. Clinical Study on Acupuncture at Zusanli,Taichong and Hegu Points Combined with Three-step Analgesic Ladder for Treatment of Gastric Cancer Pain. Journal of Guangzhou University of Traditional Chinese Medicine. 2017;3:344-7. Link

  • 米建平, 邓特伟, 周达君, 火针为主配合三阶梯止痛法治疗胃癌疼痛临床疗效观察. 辽宁中医杂志, 2010;10:2018-9. Link

  • Tan GS, Lin ZT, Wang Q, LIAO HB, LU JS, WANG T, et al. Clinical Observation on Analgesia Effect in Cancer Pain Treated with Acupuncture and Western Medicine. World Journal of Integrated Traditional and Western Medicine. 2012;2:147-9. Link

  • 钟华. 浮针辅助治疗中度癌性疼痛的疗效观察. 中华针灸电子杂志. 2016;4:148-51. Link

  • 沈淑蓉, 吴林峰. 穴位埋线配合以痛为腧针刺法治疗癌性疼痛的效果分析. 中国高等医学教育. 2018;8:134+145. Link

  • Wei YG, CP Zhou. The curative effect observation of acupoint catgut embedding to treat lung cancer pain. Prev med chin PLA [jie fang jun yu fang yi xue za zhi]. 2016;34(3):297-8. Link

  • Chen ZJ, Guo YP, Wu ZC. Observation on the therapeutic effect of acupuncture at pain points
    on cancer pain. Zhongguo Zhen Jiu. 2008;28(4):251-3. Link

  • 邓懿, 硫酸吗啡控释片联合针刺改善老年癌性疼痛患者生存质量的效果. 现代中西医结合杂志, 2015;6:606-8. Link

  • Ding QG. Clinical study of acupuncture at Mingmen and Guanyuan acupoints combined with analgesic on the treatment of lumbar spinal metastatic carcinoma pains. Chinese medicine modern distance education of china [zhong guo zhong yi yao xian dai yuan cheng jiao yu]. 2015;13(7):65-6. Link

  • 江彬, 陈峰, 邓山, 杜慧静. 针刺太冲合谷治疗癌痛25例. 浙江中医杂志. 2016:4:270. Link

  • Li DH, Sun CX, Fan HF. Clinical Study on Acupuncture at Zusanli,Taichong and Hegu Points Combined with Three-step Analgesic Ladder for Treatment of Gastric Cancer Pain. Journal of Guangzhou University of Traditional Chinese Medicine. 2017;3:344-7. Link

  • 米建平, 邓特伟, 周达君, 火针为主配合三阶梯止痛法治疗胃癌疼痛临床疗效观察. 辽宁中医杂志, 2010;10:2018-9. Link

  • Tan GS, Lin ZT, Wang Q, LIAO HB, LU JS, WANG T, et al. Clinical Observation on Analgesia Effect in Cancer Pain Treated with Acupuncture and Western Medicine. World Journal of Integrated Traditional and Western Medicine. 2012;2:147-9. Link

  • 钟华. 浮针辅助治疗中度癌性疼痛的疗效观察. 中华针灸电子杂志. 2016;4:148-51. Link

  • 沈淑蓉, 吴林峰. 穴位埋线配合以痛为腧针刺法治疗癌性疼痛的效果分析. 中国高等医学教育. 2018;8:134+145. Link

  • Wei YG, CP Zhou. The curative effect observation of acupoint catgut embedding to treat lung cancer pain. Prev med chin PLA [jie fang jun yu fang yi xue za zhi]. 2016;34(3):297-8. Link

암성 통증 환자의 주 증상 개선을 위하여 침 치료를 고려해야 한다.

암성 통증은 불안, 우울, 불면, 피로, 식욕부진 등의 증상과 복합적으로 나타날 수 있으며 종양의 직접적 원인으로 발생할 수 있으므로 다학제적 진단 및 치료의 병행을 고려해야 한다. 혈자리로는 아시혈, 배수혈, 족삼리(ST36), 합곡(LI4), 태충(LR3), 관원(CV4), 중완(CV12)을 고려할 수 있다. 치료기간은 보통 주2회-5회, 3주-8주 치료한다.

B/Low

  • Kim K, Lee S. Intradermal Acupuncture Along with Analgesics for Pain Control in Advanced Cancer Cases: A Pilot, Randomized, Patient-Assessor-Blinded, Controlled Trial. Integrative Cancer Therapies. 2018;17(4):1137–43. Link

  • Zhang Y, Zhao H, Ji WU, Wang Y, ang LU, Shen H, et al. Clinical Observations on Qin’s Scalp Eight-needle Acupuncture for the Treatment of Cancer Pain. Shanghai Journal of Acupuncture and Moxibustion. 2016;35(10):1222-5. Link

  • Alimi D, Rubino C, Pichard-Léandri E, Fermand-Brulé S, Dubreuil-Lemaire M-L, Hill C. Analgesic Effect of Auricular Acupuncture for Cancer Pain: A Randomized, Blinded, Controlled Trial. Journal of Clinical Oncology. 2003;21(22):4120–6. Link

  • Ruela LDO, Iunes DH, Nogueira DA, Stefanello J, Gradim CVC. Effectiveness of auricular acupuncture
    in the treatment of cancer pain: randomized clinical trial. Rev Esc Enferm USP. 2018;52:e03402. Link

  • Kim K, Lee S. Intradermal Acupuncture Along with Analgesics for Pain Control in Advanced Cancer Cases: A Pilot, Randomized, Patient-Assessor-Blinded, Controlled Trial. Integrative Cancer Therapies. 2018;17(4):1137–43. Link

  • Zhang Y, Zhao H, Ji WU, Wang Y, ang LU, Shen H, et al. Clinical Observations on Qin’s Scalp Eight-needle Acupuncture for the Treatment of Cancer Pain. Shanghai Journal of Acupuncture and Moxibustion. 2016;35(10):1222-5. Link

  • Alimi D, Rubino C, Pichard-Léandri E, Fermand-Brulé S, Dubreuil-Lemaire M-L, Hill C. Analgesic Effect of Auricular Acupuncture for Cancer Pain: A Randomized, Blinded, Controlled Trial. Journal of Clinical Oncology. 2003;21(22):4120–6. Link

  • Ruela LDO, Iunes DH, Nogueira DA, Stefanello J, Gradim CVC. Effectiveness of auricular acupuncture
    in the treatment of cancer pain: randomized clinical trial. Rev Esc Enferm USP. 2018;52:e03402. Link

암성 피로 환자의 주 증상 개선을 위하여 일상관리보다 십전대보탕 및 일상관리 의 병행을 고려해야 한다.

암성 피로는 다학제적 진단 및 치료의 병행을 고려해야 한다. 일상관리에는 피로교육, 식사교육, 심리치료 등의 대증지지요법이 포함된다. 치료기간은 보통 3주-8주 치료한다.

B/Moderate

  • 李家春, 简小云, 赖昕, 梁炳辉, 詹伟杰, 王敬民. 十全大补汤加减治疗对肺癌患者姑息治疗期间癌因性疲乏的影响分析. 四川中医. 2018;6:121-3. Link

  • 韩笑，迟文成，庞雪莹，唐寅，李雨. 十全大补汤加减治疗对肺癌患者姑息治疗期间癌因性疲乏的影响分析. 四川中医. 2018;6:121-3. Link

  • 李家春, 简小云, 赖昕, 梁炳辉, 詹伟杰, 王敬民. 十全大补汤加减治疗对肺癌患者姑息治疗期间癌因性疲乏的影响分析. 四川中医. 2018;6:121-3. Link

  • 韩笑，迟文成，庞雪莹，唐寅，李雨. 十全大补汤加减治疗对肺癌患者姑息治疗期间癌因性疲乏的影响分析. 四川中医. 2018;6:121-3. Link

암성 피로 환자의 주 증상 개선을 위하여 일상관리보다 보중익기탕 및 일상관리 의 병행을 고려해야 한다.

암성 피로는 다학제적 진단 및 치료의 병행을 고려해야 한다. 일상관리에는 피로교육, 식사교육, 심리치료 등의 대증지지요법이 포함된다. 치료기간은 보통 3주-8주 치료한다.

B/Low

  • 林振荣, 潘萍. 补中益气汤治疗癌因性疲乏的临床观察. 光明中医. 2018;14:2039-41. Link

  • 李军, 杨海燕. 补中益气丸治疗乳腺癌肿瘤相关性疲劳的临床观察. 辽宁医学院学报. 2015;3:12-4. Link

  • 于建华, 江正龙, 王宁军, 冯利, 王文玲. 补中益气汤改善癌因性疲乏. 吉林中医药. 2019;7:886-9. Link

  • 朱国栋, 刘丰, 朱志刚, 孙启鑫, 许昕, 陈桂萍, et al. 补中益气汤治疗胃癌化疗间期癌因性疲乏的临床观察. 现代医院. 2016;8:1169-71. Link

  • 刘永叶, 韩涛, 张双鹤, 陈威弛, 张冠中, 郑振东, et al. 补中益气汤治疗晚期肿瘤患者癌因性疲乏的临床观察. 临床误诊误治. 2016;S1:88-91. Link

  • 杨昌卫, 朱政, 陈永强, 陈钊锦, 黄秋光, 彭寿洲. 补中益气汤改善晚期恶性肿瘤患者癌因性疲乏的临床探讨. 中医临床研究. 2018;7:74-6. Link

  • 陈志成, 蔡红兵, 梁精. 补中益气汤对癌因性疲乏的影响. 右江民族医学院学报. 2017;3:217- 9. Link

  • Jong Soo Jeong, Bong Ha Ryu, Jin Sung Kim, Jae Woo Park, Won Cheol Choi, Seong Woo Yoon. Bojungikki-Tang for Cancer-Related Fatigue: A Pilot Randomized Clinical Trial. Integrative Cancer Therapies. 2010;9(4):331–8. Link

  • 林振荣, 潘萍. 补中益气汤治疗癌因性疲乏的临床观察. 光明中医. 2018;14:2039-41. Link

  • 李军, 杨海燕. 补中益气丸治疗乳腺癌肿瘤相关性疲劳的临床观察. 辽宁医学院学报. 2015;3:12-4. Link

  • 于建华, 江正龙, 王宁军, 冯利, 王文玲. 补中益气汤改善癌因性疲乏. 吉林中医药. 2019;7:886-9. Link

  • 朱国栋, 刘丰, 朱志刚, 孙启鑫, 许昕, 陈桂萍, et al. 补中益气汤治疗胃癌化疗间期癌因性疲乏的临床观察. 现代医院. 2016;8:1169-71. Link

  • 刘永叶, 韩涛, 张双鹤, 陈威弛, 张冠中, 郑振东, et al. 补中益气汤治疗晚期肿瘤患者癌因性疲乏的临床观察. 临床误诊误治. 2016;S1:88-91. Link

  • 杨昌卫, 朱政, 陈永强, 陈钊锦, 黄秋光, 彭寿洲. 补中益气汤改善晚期恶性肿瘤患者癌因性疲乏的临床探讨. 中医临床研究. 2018;7:74-6. Link

  • 陈志成, 蔡红兵, 梁精. 补中益气汤对癌因性疲乏的影响. 右江民族医学院学报. 2017;3:217- 9. Link

  • Jong Soo Jeong, Bong Ha Ryu, Jin Sung Kim, Jae Woo Park, Won Cheol Choi, Seong Woo Yoon. Bojungikki-Tang for Cancer-Related Fatigue: A Pilot Randomized Clinical Trial. Integrative Cancer Therapies. 2010;9(4):331–8. Link

암성 피로 환자의 주 증상 개선을 위하여 일상관리보다 변증을 통한 한약 치료 및 일상관리의 병행을 고려할 수 있다.

암성 피로는 다학제적 진단 및 치료의 병행을 고려해야 한다. 암성 피로에서 나타나는 다빈도의 변증유형으로는 기허, 비기허, 기혈양허, 기음양허 등이며 이에 따라서 보중익기탕, 사군자탕, 십전대보탕, 인삼양영탕 등을 고려할 수 있고 수증가감할 수 있다. 일상관리에는 피로교육, 식사교육, 심리치료 등의 대증지지요법이 포함된다. 치료기간은 보통 3주-8주 치료한다

C/Low

  • 黎汉忠, 黄智芬, 张作军, 陈闯, 谭志强, 陈蔚. 健脾消积汤治疗肝癌癌因性疲乏的临床疗效观察. 中医临床研究. 2016;10:18-20. Link

  • 楼静, 洪亮, 余飞龙. 晚期消化道肿瘤癌因性疲乏患者应用中医辨证治疗的疗效及生活质量改善状况分析. 中华中医药学刊. 2016;1:245-7. Link

  • 李家春, 简小云, 赖昕, 梁炳辉, 詹伟杰, 王敬民. 十全大补汤加减治疗对肺癌患者姑息治疗期间癌因性疲乏的影响分析. 四川中医. 2018;6:121-3. Link

  • 马婷, 王缨, 王瑾碧, 倪静, 李华. 行健汤对癌因性疲乏患者生存质量及疲乏状态的影响. 河南中医. 2015;12:3025-7. Link

  • 范晖, 张海燕, 黄兴明. 中医治疗癌症相关性乏力84例. 河南中医. 2015;7:1626-8. Link

  • 宋卿, 姜琳帅, 高静东, 李湧健. “扶正胶囊”治疗肺癌癌因性疲乏26例临床研究. 江苏中医药. 2016;12:20-2. Link

  • 严桂英. 益气养精法对改善老年非小细胞肺癌患者介入治疗后癌因性疲乏的疗效研究. 实用癌症杂志. 2018;4:588-91. Link

  • 王蕾, 谢智惠, 邬晓敏, 吕庆. 中医辨证治疗乳腺癌患者癌因性疲劳的临床观察. 中华中医药杂志. 2016;12:5375-8. Link

  • 于建华, 赵鸽, 冯利, 马银杰, 江正龙, 王宁军. 中药干预肺肾阴虚型癌因性疲乏. 中医学报.2018;11:2060-3. Link

  • 章淼, 张智敏. 加味四君子汤缓解气血不足型癌因性疲乏临床观察. 四川中医. 2019;4:91-3. Link

  • 张殿宝, 郭艳珍, 张宪芬. 贞芪扶正颗粒治疗大肠癌术后癌因性疲乏临床研究. 中医学报.2017;4:513-6. Link

  • 周岩, 田乃菊, 张法英, 李莹. 益气养阴汤辅助盐酸埃克替尼片治疗晚期非小细胞肺癌气阴两虚证患者癌因性疲乏疗效及对生活质量影响. 中国中医药信息杂志. 2020;2:13-7. Link

  • 祝永福, 夏黎明, 卢会琴. 中医辨证治疗晚期消化道肿瘤癌因性疲乏疗效观察. 中医药临床杂志. 2014;8:771-3. Link

  • 汤秀红. 参一胶囊治疗结直肠癌辅助化疗后气虚疲乏患者30例临床观察. 中医学研究.2019;35:59-60. Link

  • 郝莉莉, 刘小溪. 益气养血汤减轻胃癌患者癌症疲劳疗效及其相关细胞免疫学机制. 天津中医药. 2018;9:659-63. Link

  • 韩笑，迟文成，庞雪莹，唐寅，李雨. 十全大补汤改善肺癌患者化疗后癌因性疲乏效果及作用机制分析. 辽宁中医药大学学报. 2019;5:139-42. Link

  • 胡曾津, 廖大忠. 参白扶正颗粒对化疗后脾肾亏损型癌因性疲乏的临床研究. 收藏. 2018;5:40-1+4. Link

  • 侯恩存, 陆运鑫, 林梅英, 刘敏, 朱文良, 陈柯帆, et al. 中医治疗癌因性疲乏的临床研究. 中国医药科学. 2014;1:106- 8. Link

  • 黎汉忠, 黄智芬, 张作军, 陈闯, 谭志强, 陈蔚. 健脾消积汤治疗肝癌癌因性疲乏的临床疗效观察. 中医临床研究. 2016;10:18-20. Link

  • 楼静, 洪亮, 余飞龙. 晚期消化道肿瘤癌因性疲乏患者应用中医辨证治疗的疗效及生活质量改善状况分析. 中华中医药学刊. 2016;1:245-7. Link

  • 李家春, 简小云, 赖昕, 梁炳辉, 詹伟杰, 王敬民. 十全大补汤加减治疗对肺癌患者姑息治疗期间癌因性疲乏的影响分析. 四川中医. 2018;6:121-3. Link

  • 马婷, 王缨, 王瑾碧, 倪静, 李华. 行健汤对癌因性疲乏患者生存质量及疲乏状态的影响. 河南中医. 2015;12:3025-7. Link

  • 范晖, 张海燕, 黄兴明. 中医治疗癌症相关性乏力84例. 河南中医. 2015;7:1626-8. Link

  • 宋卿, 姜琳帅, 高静东, 李湧健. “扶正胶囊”治疗肺癌癌因性疲乏26例临床研究. 江苏中医药. 2016;12:20-2. Link

  • 严桂英. 益气养精法对改善老年非小细胞肺癌患者介入治疗后癌因性疲乏的疗效研究. 实用癌症杂志. 2018;4:588-91. Link

  • 王蕾, 谢智惠, 邬晓敏, 吕庆. 中医辨证治疗乳腺癌患者癌因性疲劳的临床观察. 中华中医药杂志. 2016;12:5375-8. Link

  • 于建华, 赵鸽, 冯利, 马银杰, 江正龙, 王宁军. 中药干预肺肾阴虚型癌因性疲乏. 中医学报.2018;11:2060-3. Link

  • 章淼, 张智敏. 加味四君子汤缓解气血不足型癌因性疲乏临床观察. 四川中医. 2019;4:91-3. Link

  • 张殿宝, 郭艳珍, 张宪芬. 贞芪扶正颗粒治疗大肠癌术后癌因性疲乏临床研究. 中医学报.2017;4:513-6. Link

  • 周岩, 田乃菊, 张法英, 李莹. 益气养阴汤辅助盐酸埃克替尼片治疗晚期非小细胞肺癌气阴两虚证患者癌因性疲乏疗效及对生活质量影响. 中国中医药信息杂志. 2020;2:13-7. Link

  • 祝永福, 夏黎明, 卢会琴. 中医辨证治疗晚期消化道肿瘤癌因性疲乏疗效观察. 中医药临床杂志. 2014;8:771-3. Link

  • 汤秀红. 参一胶囊治疗结直肠癌辅助化疗后气虚疲乏患者30例临床观察. 中医学研究.2019;35:59-60. Link

  • 郝莉莉, 刘小溪. 益气养血汤减轻胃癌患者癌症疲劳疗效及其相关细胞免疫学机制. 天津中医药. 2018;9:659-63. Link

  • 韩笑，迟文成，庞雪莹，唐寅，李雨. 十全大补汤改善肺癌患者化疗后癌因性疲乏效果及作用机制分析. 辽宁中医药大学学报. 2019;5:139-42. Link

  • 胡曾津, 廖大忠. 参白扶正颗粒对化疗后脾肾亏损型癌因性疲乏的临床研究. 收藏. 2018;5:40-1+4. Link

  • 侯恩存, 陆运鑫, 林梅英, 刘敏, 朱文良, 陈柯帆, et al. 中医治疗癌因性疲乏的临床研究. 中国医药科学. 2014;1:106- 8. Link

암성 피로 환자의 주 증상 개선을 위하여 십전대보탕을 고려해야 한다.

암성 피로는 다학제적 진단 및 치료의 병행을 고려해야 한다. 치료기간은 보통 3주-8주 치료한다.

B/Moderate

  • Lee JY, Kim EH, Yoon JH, Eo W, Yoon SW. Traditional Herbal Medicine, Sipjeondaebo-Tang, for Cancer-Related Fatigue: A Randomized, Placebo-Controlled, Preliminary Study. Integr Cancer er. 2021;20:15347354211040830. Link

  • Lee JY, Kim EH, Yoon JH, Eo W, Yoon SW. Traditional Herbal Medicine, Sipjeondaebo-Tang, for Cancer-Related Fatigue: A Randomized, Placebo-Controlled, Preliminary Study. Integr Cancer er. 2021;20:15347354211040830. Link

암성 피로 환자의 주 증상 개선을 위하여 일상관리보다 뜸 치료 및 일상관리의 병 행을 고려해야 한다.

암성 피로는 다학제적 진단 및 치료의 병행을 고려해야 한다. 일상관리에는 피로교육 및 대증지지요법 등이 포함된다. 뜸 치료로 인한 화상을 주의해야 한다. 혈자리로는 기해(CV6), 관원(CV4), 중완(CV12), 족삼리(ST36), 삼음교(SP6), 태계(KI3), 혈해(SP10), 합곡(LI4)을 고려할 수 있다. 치료기간은 보통 주2회-3회, 3주-8주 치료한다.

B/Moderate

  • 覃霄燕, 刘展华. 腹背温灸法治疗晚期癌症患者癌因性疲乏的临床研究. 中医学报. 2012;3:273-4. Link

  • 李静, 陈军. 艾灸干预晚期乳腺癌患者癌因性疲劳的临床研究. 中医临床研究. 2013;22:1-4. Link

  • 聂斌 李志明 钟旭敏 吴文锋. 扶阳火艾灸治疗阳虚型癌因性疲乏临床观察. 上海针灸杂志. 2015;6:527-30. Link

  • 吴辉渊, 郭红飞, 徐婷, 陈美玲. 热敏灸干预对中晚期肺癌患者癌因性疲乏的作用. 针灸临床杂志. 2016;7:52-4. Link

  • 于蕾, 景年财, 杨吉利, 侯艳艳, 徐蕾. 癌因性疲乏的临床特征分析及艾灸治疗的效果观察. 中国医药指南. 2012;31:591-3. Link

  • 袁敏, 张国铎, 李敏, 肖用兰, 黄晓燕. 督灸辅助治疗大肠癌术后化疗患者癌因性疲乏. 护理学杂志. 2017;32(19):8-10. Link

  • 张雪, 黄文娟, 徐天舒. 麦粒灸对恶性肿瘤患者癌因性疲乏及生活质量的影响. 上海针灸杂志. 2016;6:659-62. Link

  • 许晓洲, 祝永福, 夏黎明. 艾灸治疗脾肾亏虚型癌因性疲乏临床研究. 中医药临床杂志. 2017;5:712-5. Link

  • 覃霄燕, 刘展华. 腹背温灸法治疗晚期癌症患者癌因性疲乏的临床研究. 中医学报. 2012;3:273-4. Link

  • 李静, 陈军. 艾灸干预晚期乳腺癌患者癌因性疲劳的临床研究. 中医临床研究. 2013;22:1-4. Link

  • 聂斌 李志明 钟旭敏 吴文锋. 扶阳火艾灸治疗阳虚型癌因性疲乏临床观察. 上海针灸杂志. 2015;6:527-30. Link

  • 吴辉渊, 郭红飞, 徐婷, 陈美玲. 热敏灸干预对中晚期肺癌患者癌因性疲乏的作用. 针灸临床杂志. 2016;7:52-4. Link

  • 于蕾, 景年财, 杨吉利, 侯艳艳, 徐蕾. 癌因性疲乏的临床特征分析及艾灸治疗的效果观察. 中国医药指南. 2012;31:591-3. Link

  • 袁敏, 张国铎, 李敏, 肖用兰, 黄晓燕. 督灸辅助治疗大肠癌术后化疗患者癌因性疲乏. 护理学杂志. 2017;32(19):8-10. Link

  • 张雪, 黄文娟, 徐天舒. 麦粒灸对恶性肿瘤患者癌因性疲乏及生活质量的影响. 上海针灸杂志. 2016;6:659-62. Link

  • 许晓洲, 祝永福, 夏黎明. 艾灸治疗脾肾亏虚型癌因性疲乏临床研究. 中医药临床杂志. 2017;5:712-5. Link

암성 피로 환자의 주 증상 개선을 위하여 일상관리보다 침 치료 및 일상관리의 병 행을 고려해야 한다.

암성 피로는 다학제적 진단 및 치료의 병행을 고려해야 한다. 일상관리에는 피로교육 및 대증지지요법 등이 포함된다. 혈자리로는 기해(CV6), 관원(CV4), 중완(CV12), 족삼리(ST36), 삼음교(SP6), 태계(KI3), 혈해(SP10), 합곡(LI4)을 고려할 수 있다. 치료기간은 보통 주2회-3회, 3주-8주 치료한다.

B/Low

  • Johnston MF, Hays RD, Subramanian SK, Elasho RM, Axe EK, Li J-J, et al. Patient education integrated with acupuncture for relief of cancer-related fatigue randomized controlled feasibility study. BMC Complementary and Alternative Medicine. 2011;11(1). Link

  • Molassiotis A, Bardy J, Finnegan-John J, Mackereth P, Ryder DW, Filshie J, et al. Acupuncture for Cancer-Related Fatigue in Patients With Breast Cancer: A Pragmatic Randomized Controlled Trial. Journal of Clinical Oncology. 2012;30(36):4470–6. Link

  • Molassiotis A, Bardy J, Finnegan-John J, Mackereth P, Ryder WD, Filshie J, et al. A randomized, controlled trial of acupuncture self-needling as maintenance therapy for cancer-related fatigue after therapist-delivered acupuncture. Annals of Oncology. 2013;24(6):1645–52. Link

  • Smith C, Carmady B, ornton C, Perz J, Ussher JM. The Effect of Acupuncture on Post-Cancer Fatigue and Well-Being for Women Recovering from Breast Cancer: A Pilot Randomised Controlled Trial. Acupuncture in Medicine. 2013;31(1):9–15. Link

  • 郭莉媛, 刘淑兰, 彭艳, 于辉, 李奇, 王大鹏. 针灸对妇科肿瘤病人化疗后癌性疲劳影响的研究. 针灸临床杂志. 2014;6:67-70. Link

  • 李秀双, 付于, 于建春, 韩景献, 贾英杰, 张莹, et al. 三焦针法治疗癌性疲劳 40 例临床观察. 中医杂志. 2016;57(18):1570-3. Link

  • 苏雅, 祝永福, 夏黎明. 针刺治疗脾肾亏虚型癌因性疲乏的临床研究. 上海针灸杂志 2016:830-2. Link

  • 周猜, 田华琴, 曾白玉, 何新芳. 疲三针治疗乳腺癌患者癌因性疲乏临床观察. 收藏. 2018;6:950-3. Link

  • 陈军, 方乃青, 王蕾, 邬晓敏, 肖寒, 孙春雷. 针刺治疗乳腺癌患者癌因性疲乏 30 例临床研究. 江苏中医药. 2016;48(12):56-8. Link

  • Johnston MF, Hays RD, Subramanian SK, Elasho RM, Axe EK, Li J-J, et al. Patient education integrated with acupuncture for relief of cancer-related fatigue randomized controlled feasibility study. BMC Complementary and Alternative Medicine. 2011;11(1). Link

  • Molassiotis A, Bardy J, Finnegan-John J, Mackereth P, Ryder DW, Filshie J, et al. Acupuncture for Cancer-Related Fatigue in Patients With Breast Cancer: A Pragmatic Randomized Controlled Trial. Journal of Clinical Oncology. 2012;30(36):4470–6. Link

  • Molassiotis A, Bardy J, Finnegan-John J, Mackereth P, Ryder WD, Filshie J, et al. A randomized, controlled trial of acupuncture self-needling as maintenance therapy for cancer-related fatigue after therapist-delivered acupuncture. Annals of Oncology. 2013;24(6):1645–52. Link

  • Smith C, Carmady B, ornton C, Perz J, Ussher JM. The Effect of Acupuncture on Post-Cancer Fatigue and Well-Being for Women Recovering from Breast Cancer: A Pilot Randomised Controlled Trial. Acupuncture in Medicine. 2013;31(1):9–15. Link

  • 郭莉媛, 刘淑兰, 彭艳, 于辉, 李奇, 王大鹏. 针灸对妇科肿瘤病人化疗后癌性疲劳影响的研究. 针灸临床杂志. 2014;6:67-70. Link

  • 李秀双, 付于, 于建春, 韩景献, 贾英杰, 张莹, et al. 三焦针法治疗癌性疲劳 40 例临床观察. 中医杂志. 2016;57(18):1570-3. Link

  • 苏雅, 祝永福, 夏黎明. 针刺治疗脾肾亏虚型癌因性疲乏的临床研究. 上海针灸杂志 2016:830-2. Link

  • 周猜, 田华琴, 曾白玉, 何新芳. 疲三针治疗乳腺癌患者癌因性疲乏临床观察. 收藏. 2018;6:950-3. Link

  • 陈军, 方乃青, 王蕾, 邬晓敏, 肖寒, 孙春雷. 针刺治疗乳腺癌患者癌因性疲乏 30 例临床研究. 江苏中医药. 2016;48(12):56-8. Link

암성 피로 환자의 주 증상 개선을 위하여 전침 치료를 고려해야 한다.

암성 피로는 다학제적 진단 및 치료의 병행을 고려해야 한다. 혈자리로는 기해(CV6), 관원(CV4), 중완(CV12), 족삼리(ST36), 삼음교(SP6), 태계(KI3), 혈해(SP10), 합곡(LI4)을 고려할 수 있다. 치료기간은 보통 주2회-3회, 3주-8주 치료한다.

B/Moderate

  • Hou L, Zhou C, Wu Y, Yu Y, Hu Y. Transcutaneous electrical acupoint stimulation (TEAS) relieved
    cancer-related fatigue in non-small cell lung cancer (NSCLC) patients after chemotherapy. Journal of oracic Disease. 2017;9(7):1959–66. Link

  • Mao JJ, Farrar JT, Bruner D, Zee J, Bowman M, Seluzicki C, et al. Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor‐related arthralgia: A randomized trial. Cancer. 2014;120(23):3744–51. Link

  • Hou L, Zhou C, Wu Y, Yu Y, Hu Y. Transcutaneous electrical acupoint stimulation (TEAS) relieved
    cancer-related fatigue in non-small cell lung cancer (NSCLC) patients after chemotherapy. Journal of oracic Disease. 2017;9(7):1959–66. Link

  • Mao JJ, Farrar JT, Bruner D, Zee J, Bowman M, Seluzicki C, et al. Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor‐related arthralgia: A randomized trial. Cancer. 2014;120(23):3744–51. Link

  • Hou L, Zhou C, Wu Y, Yu Y, Hu Y. Transcutaneous electrical acupoint stimulation (TEAS) relieved
    cancer-related fatigue in non-small cell lung cancer (NSCLC) patients after chemotherapy. Journal of oracic Disease. 2017;9(7):1959–66. Link

  • Mao JJ, Farrar JT, Bruner D, Zee J, Bowman M, Seluzicki C, et al. Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor‐related arthralgia: A randomized trial. Cancer. 2014;120(23):3744–51. Link

암성 피로 환자의 주 증상 개선을 위하여 침 치료를 고려해야 한다.

암성 피로는 불안, 우울, 불면, 통증, 식욕부진 등의 증상과 복합적으로 나타날 수 있으며 영양부족, 빈혈, 통증 등에 대한 처치가 필요할 수 있으므로 다학제적 진단 및 치료의 병행을 고려해야 한다. 혈자리로는 기해(CV6), 관원(CV4), 중완(CV12), 족삼리(ST36), 삼음교(SP6), 태계(KI3), 혈해(SP10), 합곡(LI4)을 고려할 수 있다. 치료기간은 보통 주2회-3회, 3주-8주 치료한다.

B/Moderate

  • Cheng C-shan, Chen L-yu, Ning Z-yu, Zhang C-yue, Chen H, Chen Z, et al. Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial. Supportive Care in Cancer. 2017;25(12):3807–14. Link

  • Deng G, Chan Y, Sjoberg D, Vickers A, Yeung KS, Kris M, et al. Acupuncture for the treatment of post-chemotherapy chronic fatigue: a randomized, blinded, sham-controlled trial. Supportive
    Care in Cancer. 2013;21(6):1735–41. Link

  • Smith C, Carmady B, ornton C, Perz J, Ussher JM. The Effect of Acupuncture on Post-Cancer Fatigue and Well-Being for Women Recovering from Breast Cancer: A Pilot Randomised Controlled Trial. Acupuncture in Medicine. 2013;31(1):9–15. Link

  • 于明薇, 李道睿, 杨国旺, 徐咏梅, 王笑民. 针刺治疗康复期乳腺癌患者癌因性疲乏的随机对照研究. 中国医药导报. 2017;14(19):89-93. Link

  • Cheng C-shan, Chen L-yu, Ning Z-yu, Zhang C-yue, Chen H, Chen Z, et al. Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial. Supportive Care in Cancer. 2017;25(12):3807–14. Link

  • Deng G, Chan Y, Sjoberg D, Vickers A, Yeung KS, Kris M, et al. Acupuncture for the treatment of post-chemotherapy chronic fatigue: a randomized, blinded, sham-controlled trial. Supportive
    Care in Cancer. 2013;21(6):1735–41. Link

  • Smith C, Carmady B, ornton C, Perz J, Ussher JM. The Effect of Acupuncture on Post-Cancer Fatigue and Well-Being for Women Recovering from Breast Cancer: A Pilot Randomised Controlled Trial. Acupuncture in Medicine. 2013;31(1):9–15. Link

  • 于明薇, 李道睿, 杨国旺, 徐咏梅, 王笑民. 针刺治疗康复期乳腺癌患者癌因性疲乏的随机对照研究. 中国医药导报. 2017;14(19):89-93. Link

  • Cheng C-shan, Chen L-yu, Ning Z-yu, Zhang C-yue, Chen H, Chen Z, et al. Acupuncture for cancer-related fatigue in lung cancer patients: a randomized, double blind, placebo-controlled pilot trial. Supportive Care in Cancer. 2017;25(12):3807–14. Link

  • Deng G, Chan Y, Sjoberg D, Vickers A, Yeung KS, Kris M, et al. Acupuncture for the treatment of post-chemotherapy chronic fatigue: a randomized, blinded, sham-controlled trial. Supportive
    Care in Cancer. 2013;21(6):1735–41. Link

  • Smith C, Carmady B, ornton C, Perz J, Ussher JM. The Effect of Acupuncture on Post-Cancer Fatigue and Well-Being for Women Recovering from Breast Cancer: A Pilot Randomised Controlled Trial. Acupuncture in Medicine. 2013;31(1):9–15. Link

  • 于明薇, 李道睿, 杨国旺, 徐咏梅, 王笑民. 针刺治疗康复期乳腺癌患者癌因性疲乏的随机对照研究. 中国医药导报. 2017;14(19):89-93. Link



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